...Good morning, everyone. Thank you for joining the 21st Annual Needham Healthcare Conference. My name is Joey Stringer, and I'm one of the biotech analysts at Needham & Company. It's my pleasure to introduce our next presenting company, Ionis Pharmaceuticals. And joining us today from Ionis is EVP of Research, Eric Swayze. For those of you joining on the webcast, if you want to ask a question, please do so at any time. You can submit a question using the chat box at the bottom of your screen. With that, we'll go ahead and get started. Eric, thank you so much for joining us today. Eric E. Swayze ...