...Good afternoon and good evening, everybody. Thanks for joining us for our final company presenter at the BofA Global Healthcare Conference. My name is Jason Gerberry, smid-cap biotech analyst at BofA. And I'm pleased to be introducing Ionis and Brett Monia, CEO of Ionis. And Ionis, for those of you on the line who don't know, is a leader in antisense oligonucleotide therapeutics, or ASOs as we may refer to them on the call. So first off, Brett, thanks for joining us. Brett P. Monia ...