...Good afternoon, everybody. Thanks for joining us for the next session. I'm Matthew Harrison, one of the biotech analysts here at Morgan Stanley. Very pleased to have Sage Therapeutics with us. Quickly before we get started, I need to read a disclosure statement. Please note that all important disclosures, including personal holdings disclosures and Morgan Stanley disclosures, appear on the Morgan Stanley public website at morganstanley.com/researchdisclosures. And with that, pleased to turn it over to Barry Greene, the CEO, to make some opening comments and then we'll jump into Q&A. Barry E. Greene ...