...Good afternoon, everyone. Thanks for joining us. We're really pleased to have with us Brett Monia, CEO of Ionis. Before we start, though, I'm going to read a disclosure. We are required to make certain disclosures and public appearances about Goldman Sachs relationships with companies that we discuss. The disclosures relate to investment banking relationships, compensation received or 1% or more ownership. We are prepared to read a lot of disclosures for any issuer during the sessions upon your request. However, these disclosures are available in our most recent reports to view [client on firm] portals. In addition, updates to these disclosures are available by ticker on the firm's public website. Goldman Sachs agrees to host this conference on the basis that no third-party speaker will provide confidential and material nonpublic information. In addition, by attending the conference, you provide Goldman Sachs the right to rerecord or record and redistribute the conference information to...
