...(technical difficulty) My name is Brett Monia. I'm the CEO of Ionis. I'm very pleased to provide an update on Ionis for you today, and I'm very pleased that all of you are joining us for today's presentation. Before I get started, I would like to first announce for our shareholders some changes to the Ionis Board of Directors, starting with -- I'm sorry, starting with Stan Crooke. Stan Crooke, after today, will be stepping down from the Ionis Board of Directors. Stan, of course, is the founder of Ionis Pharmaceuticals and has served as the CEO and Executive Chairman for over 30 years at Ionis. And more than that, he provided 30 years of outstanding leadership to the company. We'll very much miss Stan going forward, but we're very pleased by the fact that Stan will be continuing to serve on Ionis as a scientific adviser going forward. In addition, Breaux Castleman, after 8 years of outstanding contributions to Ionis as a Board director and as a member of the Audit Committee, will also be...