The following is excerpted from the question-and-answer section of the transcript.
(Questions from industry analysts are provided in full, but answers are omitted - download the transcript to see the full question-and-answer session)
Question: David Lebowitz - Citigroup Inc - Analyst
: Thank you very much for that. I appreciate it. I'll unmute myself here. Certainly, cabozantinib has been backbone for the company
and for quite a while and renal cell carcinoma has been a big part of that. Could you walk us through the current treatment landscape
in renal cell carcinoma, talk about the role that cabo has served is currently serving and how you expect that role might evolve going
forward?
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FEBRUARY 19, 2025 / 7:00PM, EXEL.OQ - Exelixis Inc at Citi Virtual Oncology Leadership Summit
Question: David Lebowitz - Citigroup Inc - Analyst
: So you mentioned that, certainly, that's going to be an important topic in the next month or so, given the FDA's imminent decision.
Could you run us through what was presented in the net beta in the cabinet trial to this point. And what we should take away from
it as far as the potential in that particular population?
Question: David Lebowitz - Citigroup Inc - Analyst
: So given how heterogeneous the population is how are they currently treated today and how you expect that might change? And
as we look towards this approval, what is the opportunity actually represent? How large?
Question: David Lebowitz - Citigroup Inc - Analyst
: What type of cadence could we see with the penetration and do it given how heterogeneous the market is, will it be more gradual?
Question: David Lebowitz - Citigroup Inc - Analyst
: And let's jump over to prostate cancer. We do update us and tell us about the COMPACT-02 data and where things stand on that
end?
Question: David Lebowitz - Citigroup Inc - Analyst
: Got it. Let's jump over to zanza. I guess to start, how is it similar and how is it different from cabo?
Question: David Lebowitz - Citigroup Inc - Analyst
: So we have some pivotal data coming up in the second half of the year. Could you set the stage for what we should expect from
each of those studies?
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FEBRUARY 19, 2025 / 7:00PM, EXEL.OQ - Exelixis Inc at Citi Virtual Oncology Leadership Summit
Question: David Lebowitz - Citigroup Inc - Analyst
: We are getting close to the end here. Last question here, a little free for all for you. What's next? What do you want to tell us about
what we can expect in the future?
Question: David Lebowitz - Citigroup Inc - Analyst
: Excellent. Thanks again for coming today, and we look forward to chatting again soon.
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