The following is excerpted from the question-and-answer section of the transcript.
(Questions from industry analysts are provided in full, but answers are omitted - download the transcript to see the full question-and-answer session)
Question: Michael Ulz - Morgan Stanley - Analyst
: No, that was a good introduction and clarified a couple of things. Maybe a few follow-ups. Maybe just one on the leadership changes. Are there
any plans to make future changes or are we kind of in the right spot for now?
REFINITIV STREETEVENTS | www.refinitiv.com | Contact Us
consent of Refinitiv. 'Refinitiv' and the Refinitiv logo are registered trademarks of Refinitiv and its affiliated companies.
SEPTEMBER 05, 2024 / 8:05PM, DYN.OQ - Dyne Therapeutics Inc at Morgan Stanley Global Healthcare
Conference
Question: Michael Ulz - Morgan Stanley - Analyst
: Maybe we can just switch to the DMD data. And you brought it up, just the two patients that experience the safety. Can you maybe just give us a
little bit more details on that and why that is or isn't concerning?
Question: Michael Ulz - Morgan Stanley - Analyst
: Maybe just a quick follow-up. Just given that it's considered most likely unrelated, you've obviously dropped the dose, but are there other things
you can do to maybe mitigate this potential risk in the future? Or any thoughts around that?
Question: Michael Ulz - Morgan Stanley - Analyst
: Could you decide to go up on the dose in the future and what might be some of the considerations that lead you to do that?
Question: Michael Ulz - Morgan Stanley - Analyst
: Can you maybe talk about just next steps from the program from here and when we might get another update?
Question: Michael Ulz - Morgan Stanley - Analyst
: Makes sense. How do you think about expanding beyond exon 51 into sort of other exon?
Question: Michael Ulz - Morgan Stanley - Analyst
: John, you talked about rapidly sort of advancing the program. Maybe just talk commercially. I know we're a little bit away from that, but just the
impact of gene therapy and how exon skippers can kind of fit into that paradigm?
Question: Michael Ulz - Morgan Stanley - Analyst
: Makes sense. Maybe we can shift gears a little bit just to DM1. And I think you're going to present an update later this year. So maybe just kind of
remind us what you've shown so far and what we should expect.
Question: Michael Ulz - Morgan Stanley - Analyst
: Maybe just quickly, last minute, just the current thinking on the regulatory path forward. I know you're going to give us specifics, but just what are
kind of the options at this point?
Question: Michael Ulz - Morgan Stanley - Analyst
: Okay, great. We're out of time, unfortunately. Thanks so much, John, Doug, and Wildon. Really appreciate your time.
|