The following is excerpted from the question-and-answer section of the transcript.
(Questions from industry analysts are provided in full, but answers are omitted - download the transcript to see the full question-and-answer session)
Question: Steve Scala - TD Cowen - Analyst
: <_ALACRA_META_ABSTRACT>Let's start out maybe with, I think you were going to start out with kind of some brief opening remarks and maybe include in that
some of the pushes and pulls of the Medicare Part D redesign as part of the answer.
Question: Steve Scala - TD Cowen - Analyst
: And one more question on this topic, and that is, talk about the phasing in 2025. So how does this redesign impact the sequence of
the year?
Question: Steve Scala - TD Cowen - Analyst
: Just so I can kind of figure this out in my own head, so let's say ELIQUIS US does for the sake of argument, $10 billion this year, is a
starting point $2.5 billion per quarter? Is that the way to look at it or how would you alter those numbers?
Question: Steve Scala - TD Cowen - Analyst
: By the way, if there's questions anywhere along the line, please just raise your hand and we'll pose your question.
So let's go to COBENFY. One of the most exciting rollouts in the industry in 2025. Do you think COBENFY can reach blockbuster status
within two to three years post launch?
Question: Steve Scala - TD Cowen - Analyst
: You've mentioned the better than expected access or accesses ahead of expectations. But what has driven that? Is it the inherent
profile of the drug and payers realize they have to cover it, or is it that Bristol-Myers Squibb is giving terms that just make it attractive
or some combination?
Question: Steve Scala - TD Cowen - Analyst
: What is the biggest hurdle for COBENFY in the marketplace? Is it step through of generic antipsychotics, or is it competition from
branded products, or is it something else?
Question: Steve Scala - TD Cowen - Analyst
: Questions from the audience?
Maybe we could talk about CAMZYOS. So we have this April PDUFA date to loosen the REMS program. What should be our expectation
for the trajectory of the product once that is crossed and successfully the labels changed? So what will change relative to the product
usage?
Question: Steve Scala - TD Cowen - Analyst
: So we should definitely see some sort of an inflection once the REMS is loosened.
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Question: Steve Scala - TD Cowen - Analyst
: Let's stick with CAMZYOS. One more question. And that is should it succeed in the non-obstructive HCM area? How would you think
about the market opportunity? How does it change?
Question: Steve Scala - TD Cowen - Analyst
: Questions on CAMZYOS before we go on to another topic?
You've been asked this question I think several times in the last three or four weeks, and that is Opdivo Sub-Q. We know it's early
and you've said it's early. But is it no longer that early that you could give us some characterization of the types of patients, which is
what tumors are being prescribed for this and so forth?
Question: Steve Scala - TD Cowen - Analyst
:
Question: Steve Scala - TD Cowen - Analyst
: Merck thinks they'll get roughly the same conversion in 12 to 18 months. Either they're too optimistic or you're too conservative.
Can you talk about why your conversion might take much longer than their?
Question: Steve Scala - TD Cowen - Analyst
: Sticking with Opdivo , how are launch preparations for Opdivo plus Yervoy in first line HCC going?
Question: Steve Scala - TD Cowen - Analyst
: Moving to SOTYKTU. Does it still have blockbuster potential in your eyes?
Question: Steve Scala - TD Cowen - Analyst
: Questions from the audience?
Maybe zooming out a little bit. Has there been any evidence of bleed through of IRA pricing to the commercial setting as you've
gone through the contracting cycle?
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Question: Steve Scala - TD Cowen - Analyst
: It is a little bit impressive that the male vaccine studies are expected to end on time based on what is now known, at least, whereas
other major cardiovascular trials get pushed out and they seem to be getting pushed out on an accelerating basis rate, but for some
reason the Bristol studies are right on time. So what do you attribute that?
Question: Steve Scala - TD Cowen - Analyst
: I guess I should have been able to conclude that on my own, but I didn't didn't.
So when Bay left this field, did your recruit And go up a lot. It's so, okay, so there's a lot more events being accumulated more quickly.
It.
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Question: Steve Scala - TD Cowen - Analyst
: Okay, I know Bristol tends to be conservative and doesn't want to get over its skis, but that might also argue that the study could
end early, which I know the company won't speak to. But okay, let's talk about your radio ligand therapy. What targets tumors and
molecules are you exploring exploring with radio ligand therapy?
Question: Steve Scala - TD Cowen - Analyst
: So we're down to mere seconds.
One more question, and that is, what product in Bristol's early development that you don't really talk about with investors are you
most excited about?
Question: Steve Scala - TD Cowen - Analyst
: Of exciting stuff going on at Bristol Myers Squib. So thank you for the rundown.
Thank you.
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