Sections
| Title | Starting Page | Number of Pages |
|---|
| 1 Table of Contents | 2 | 4 |
| 1.1 List of Tables | 4 | 1 |
| 1.2 List of Figures | 5 | 1 |
| 2 Introduction | 6 | 1 |
| 2.1 Shoulder Replacement Overview | 6 | 1 |
| 3 Products under Development | 7 | 5 |
| 3.1 Shoulder Replacement - Pipeline Products by Stage of Development | 7 | 1 |
| 3.2 Shoulder Replacement - Pipeline Products by Segment | 8 | 1 |
| 3.3 Shoulder Replacement - Pipeline Products by Territory | 9 | 1 |
| 3.4 Shoulder Replacement - Pipeline Products by Regulatory Path | 10 | 1 |
| 3.5 Shoulder Replacement - Pipeline Products by Estimated Approval Date | 11 | 1 |
| 4 Shoulder Replacement - Pipeline Products under Development by Companies | 12 | 2 |
| 4.1 Shoulder Replacement Companies - Pipeline Products by Stage of Development | 12 | 1 |
| 4.2 Shoulder Replacement - Pipeline Products by Stage of Development | 13 | 1 |
| 5 Shoulder Replacement Companies and Product Overview | 14 | 22 |
| 5.1 BioPoly RS LLC Company Overview | 14 | 1 |
| 5.1.1 BioPoly RS LLC Pipeline Products &Ongoing Clinical Trials Overview | 14 | 1 |
| 5.2 DePuy Synthes, Inc. Company Overview | 15 | 1 |
| 5.2.1 DePuy Synthes, Inc. Pipeline Products &Ongoing Clinical Trials Overview | 15 | 3 |
| 5.3 Exactech, Inc. Company Overview | 18 | 1 |
| 5.3.1 Exactech, Inc. Pipeline Products &Ongoing Clinical Trials Overview | 18 | 4 |
| 5.4 Imperial College London Company Overview | 22 | 1 |
| 5.4.1 Imperial College London Pipeline Products &Ongoing Clinical Trials Overview | 22 | 1 |
| 5.5 Integra LifeSciences Holdings Corporation Company Overview | 23 | 1 |
| 5.5.1 Integra LifeSciences Holdings Corporation Pipeline Products &Ongoing Clinical Trials Overview | 23 | 4 |
| 5.6 Medical Bionics Inc. Company Overview | 27 | 1 |
| 5.6.1 Medical Bionics Inc. Pipeline Products &Ongoing Clinical Trials Overview | 27 | 1 |
| 5.7 Orbis Medisch Centrum Company Overview | 28 | 1 |
| 5.7.1 Orbis Medisch Centrum Pipeline Products &Ongoing Clinical Trials Overview | 28 | 1 |
| 5.8 Shoulder Options, Inc. Company Overview | 29 | 1 |
| 5.8.1 Shoulder Options, Inc. Pipeline Products &Ongoing Clinical Trials Overview | 29 | 3 |
| 5.9 Topsfield Medical GmbH Company Overview | 32 | 1 |
| 5.9.1 Topsfield Medical GmbH Pipeline Products &Ongoing Clinical Trials Overview | 32 | 1 |
| 5.10 University of Missouri Company Overview | 33 | 1 |
| 5.10.1 University of Missouri Pipeline Products &Ongoing Clinical Trials Overview | 33 | 1 |
| 5.11 Zimmer Biomet Holdings, Inc. Company Overview | 34 | 1 |
| 5.11.1 Zimmer Biomet Holdings, Inc. Pipeline Products &Ongoing Clinical Trials Overview | 34 | 2 |
| 6 Shoulder Replacement- Recent Developments | 36 | 29 |
| 6.1 Oct 18, 2016: Ortho Regenerative Technologies announces changes in executive leadership | 36 | 1 |
| 6.2 Oct 12, 2016: New Studies Support Exactech s Knee, Shoulder and Computer-Assisted Surgery Technologies | 36 | 2 |
| 6.3 Oct 05, 2016: Henry Ford Health System Announces New CEO of Health Alliance Plan | 38 | 1 |
| 6.4 Sep 29, 2016: Exactech Announces Successful First Surgeries With New ExactechGPS Total Shoulder Application | 38 | 1 |
| 6.5 Sep 23, 2016: RMS Medical Products Posts Second Quarter 2017 Results | 39 | 1 |
| 6.6 Aug 03, 2016: Ortho Regenerative Technologies Raises USD0.4 Million in First Tranche of Private Placement of Units | 40 | 1 |
| 6.7 Aug 02, 2016: Corin Group and FX Solutions enter strategic partnership in the US | 40 | 1 |
| 6.8 Aug 01, 2016: Exactech Q2 Revenue Up 8% to $66.1 Million; Net Income up 20% to $4.4 Million; Diluted EPS $0.31 vs. $0.26 | 40 | 1 |
| 6.9 Jul 28, 2016: Smith &Nephew Second Quarter Trading and First Half 2016 Results | 41 | 3 |
| 6.10 Jul 28, 2016: Zimmer Biomet Reports Second Quarter 2016 Financial Results | 44 | 1 |
| 6.11 Jul 28, 2016: Integra LifeSciences Reports Second Quarter 2016 Financial Results | 45 | 1 |
| 6.12 Jul 21, 2016: Stryker reports second quarter 2016 results | 46 | 1 |
| 6.13 Jul 11, 2016: CFO to leave Smith &Nephew in early 2017 | 47 | 1 |
| 6.14 Jun 30, 2016: Ortho Regenerative Technologies appoints new CFO | 48 | 1 |
| 6.15 Jun 29, 2016: New chairman appointed at JRI Orthopaedics | 48 | 1 |
| 6.16 Jun 17, 2016: New Study Reveals Hip Arthroscopy Effective Treatment For Hip Impingement: Outcome Varies Depending On Patient's Age And Sex | 49 | 1 |
| 6.17 Jun 13, 2016: Zimmer Biomet Raises USD1.28 Billion in Public Offering of Shares | 49 | 1 |
| 6.18 Jun 07, 2016: Zimmer Biomet Plans to Raise USD750 Million in Public Offering of Notes | 50 | 1 |
| 6.19 May 23, 2016: Integra LifeSciences launches Integra Fin-Lock Glenoid for the Titan Modular Shoulder System | 50 | 1 |
| 6.20 Apr 28, 2016: Zimmer Biomet Holdings Reports First Quarter 2016 Financial Results | 50 | 1 |
| 6.21 Apr 26, 2016: Exactech Q1 Revenue Up 6% to $65.3 Million. Net Income of $4.4 Million. Diluted EPS $0.31 vs. $0.29 | 51 | 1 |
| 6.22 Apr 25, 2016: Zimmer Biomet Acquires Cayenne Medical | 52 | 1 |
| 6.23 Apr 20, 2016: Stryker reports first quarter 2016 results | 52 | 1 |
| 6.24 Apr 18, 2016: Henry Ford Breast Cancer Program Granted 3-Year Accreditation | 53 | 1 |
| 6.25 Apr 05, 2016: Allegiance Health Joins Henry Ford Health System | 53 | 1 |
| 6.26 Apr 04, 2016: Arthrex Recognized by American Heart Association as a Platinum Fit-Friendly Worksite | 54 | 1 |
| 6.27 Mar 10, 2016: Exactech Announces Completion of Corporate Integrity Agreement Requirements | 55 | 1 |
| 6.28 Mar 03, 2016: Stryker Raises USD750 Million in Public Offering of 2% Notes Due 2019 | 55 | 1 |
| 6.29 Mar 03, 2016: Stryker Raises USD1 Billion in Public Offering of 4.625% Notes Due 2046 | 55 | 1 |
| 6.30 Mar 03, 2016: Stryker Raises USD1 Billion in Public Offering of 3.5% Notes Due 2026 | 56 | 1 |
| 6.31 Mar 03, 2016: Stryker Raises USD750 Million in Public Offering of 2.625% Notes Due 2021 | 56 | 1 |
| 6.32 Mar 02, 2016: Wright Medical Group Highlights Recent Innovation SIMPLICITI Shoulder System at the American Academy of Orthopaedic Surgeons 2016 Annual Meeting | 56 | 1 |
| 6.33 Mar 01, 2016: Exactech Innovations Simplify the Complexity of Revision Total Joint Replacement | 57 | 1 |
| 6.34 Feb 18, 2016: Materialise Enters into Agreement with Mathys | 57 | 1 |
| 6.35 Feb 16, 2016: Exactech 2015 Revenue $241.8 Million, Net Income $14.8 Million, EPS $1.04 | 58 | 1 |
| 6.36 Jan 28, 2016: Zimmer Biomet Holdings Reports Fourth Quarter and Full-Year 2015 Financial Results | 59 | 1 |
| 6.37 Jan 26, 2016: Stryker Reports 2015 Results and 2016 Outlook | 59 | 1 |
| 6.38 Jan 26, 2016: Stryker Announces the Retirement of William R. Jellison and the promotion of Glenn S. Boehnlein to Vice President, Chief Financial Officer | 60 | 1 |
| 6.39 Jan 12, 2016: Stryker Provides 2015 Preliminary Sales Results and Increases Adjusted Earnings Guidance | 61 | 1 |
| 6.40 Dec 23, 2015: EQT to Acquire Limacorporate from Ardian | 62 | 1 |
| 6.41 Dec 09, 2015: Manitex Capital affiliate, Ortho Regenerative Technologies, announces the appointment of Dr. Ed Margerrison as President and CEO | 62 | 1 |
| 6.42 Oct 29, 2015: Zimmer Biomet Holdings Reports Third Quarter 2015 Financial Results | 62 | 1 |
| 6.43 Oct 27, 2015: Exactech Q3 2015 Revenue $56.2 Million. Net Income $2.9 Million. Diluted EPS $0.20 | 63 | 2 |
| 7 Appendix | 65 | 4 |
| 7.1 Methodology | 65 | 2 |
| 7.2 About GlobalData | 67 | 1 |
| 7.3 Contact Us | 67 | 1 |
| 7.4 Disclaimer | 68 | 1 |
