Hypercholesterolemia - Pipeline Review, H2 2016 - Global Markets Direct - Market Research

Hypercholesterolemia - Pipeline Review, H2 2016

Hypercholesterolemia - Pipeline Review, H2 2016 - Global Markets Direct - Market Research
Hypercholesterolemia - Pipeline Review, H2 2016
Published Nov 23, 2016
214 pages — Published Nov 23, 2016
Price US$ 2,000.00  |  Buy this Report Now

About This Report

  
Abstract:

Summary

Global Markets Direct's latest Pharmaceutical and Healthcare disease pipeline guide Hypercholesterolemia Pipeline Review, H2 2016, provides an overview of the Hypercholesterolemia (Metabolic Disorders) pipeline landscape.

Hypercholesterolemia arises due to high levels of cholesterol in the blood. These abnormal levels may lead to various diseases especially cardiovascular diseases. Cholesterol deposit in the arteries and may cause the narrowing of blood vessels hence restricting the blood flow. The predisposing factors for hypercholesterolemia include various diseases such as diabetes mellitus, renal diseases, obesity etc. The other factors involved are heredity, certain drugs, sedentary lifestyle, smoking, alcoholism, stress and high fat diet. The symptoms for hypercholesterolemia include blocked arteries, leg pain, chest pain and cholesterol deposits. The disease can be controlled by lifestyle changes, dietary changes, and medications.

Report Highlights

Global Markets Direct's Pharmaceutical and Healthcare latest pipeline guide Hypercholesterolemia Pipeline Review, H2 2016, provides comprehensive information on the therapeutics under development for Hypercholesterolemia (Metabolic Disorders), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Hypercholesterolemia (Metabolic Disorders) pipeline guide also reviews of key players involved in therapeutic development for Hypercholesterolemia and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I, IND/CTA Filed, Preclinical, Discovery and Unknown stages are 11, 13, 5, 1, 17, 8 and 1 respectively. Similarly, the Universities portfolio in Preclinical and Discovery stages comprises 7 and 2 molecules, respectively.Hypercholesterolemia.

Hypercholesterolemia (Metabolic Disorders) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from Global Markets Directs proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope

- The pipeline guide provides a snapshot of the global therapeutic landscape of Hypercholesterolemia (Metabolic Disorders).
- The pipeline guide reviews pipeline therapeutics for Hypercholesterolemia (Metabolic Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources.
- The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
- The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
- The pipeline guide reviews key companies involved in Hypercholesterolemia (Metabolic

  
Source:
Document ID
GMDHC8697IDB
Industry
Format:
PDF Adobe Acrobat
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Sections

TitleStarting PageNumber of Pages
Table of Contents211
  List of Tables111
  List of Figures121
Introduction131
  Global Markets Direct Report Coverage131
Hypercholesterolemia Overview141
Therapeutics Development152
  Pipeline Products for Hypercholesterolemia Overview151
  Pipeline Products for Hypercholesterolemia Comparative Analysis161
Hypercholesterolemia Therapeutics under Development by Companies173
Hypercholesterolemia Therapeutics under Investigation by Universities/Institutes201
Hypercholesterolemia Pipeline Products Glance214
  Late Stage Products211
  Clinical Stage Products221
  Early Stage Products231
  Unknown Stage Products241
Hypercholesterolemia Products under Development by Companies254
Hypercholesterolemia Products under Investigation by Universities/Institutes291
Hypercholesterolemia Companies Involved in Therapeutics Development3037
  3SBio Inc301
  AFFiRiS AG311
  Akcea Therapeutics Inc321
  Alvogen Korea Co Ltd331
  ARMO Biosciences Inc341
  AstraZeneca Plc351
  BioLingus AG361
  Catabasis Pharmaceuticals Inc371
  Chong Kun Dang Pharmaceutical Corp381
  CymaBay Therapeutics Inc391
  Daewon Pharm Co Ltd401
  Dicerna Pharmaceuticals Inc411
  Dybly AG421
  Esperion Therapeutics Inc431
  Gemphire Therapeutics Inc441
  Golden Biotechnology Corp451
  Hanmi Pharmaceuticals Co Ltd461
  Immune Response BioPharma Inc471
  Johnson &Johnson481
  Kadmon Corp LLC491
  Kyorin Pharmaceutical Co Ltd501
  Leading BioSciences Inc511
  LipimetiX Development Inc521
  Lotus Pharmaceutical Co Ltd531
  Merck &Co Inc541
  Pfizer Inc551
  Planet Biotechnology Inc561
  Progenra Inc571
  Regeneron Pharmaceuticals Inc581
  RegenxBio Inc591
  Serometrix LLC601
  Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co Ltd611
  Solvotrin Therapeutics Ltd621
  The Medicines Company631
  Thetis Pharmaceuticals LLC641
  Viking Therapeutics Inc651
  Zhejiang Hisun Pharmaceutical Co Ltd661
Hypercholesterolemia Therapeutics Assessment6712
  Assessment by Monotherapy Products671
  Assessment by Combination Products681
  Assessment by Target693
  Assessment by Mechanism of Action723
  Assessment by Route of Administration752
  Assessment by Molecule Type772
Drug Profiles79108
  (aspirin + lisinopril + lovastatin) Drug Profile791
  (atorvastatin calcium + ezetimibe) Drug Profile801
  (atorvastatin calcium + ezetimibe) Drug Profile811
  (atorvastatin calcium + TP-452) Drug Profile821
  (bempedoic acid + ezetimibe) Drug Profile831
  (candesartan cilexetil + rosuvastatin calcium) Drug Profile841
  (ezetimibe + rosuvastatin calcium) Drug Profile851
  AEM-28 Drug Profile862
  AEM-2802 Drug Profile881
  AEM-2814 Drug Profile891
  alirocumab Drug Profile9011
  AM-0010 Drug Profile1013
  anacetrapib Drug Profile1042
  Antibodies for Metabolic Disorders Drug Profile1061
  Antisense Oligonucleotide to Inhibit PCSK9 for Hypercholesterolemia Drug Profile1071
  Antisense Oligonucleotides to Inhibit ApoB100 for Familial Hypercholesterolemia Drug Profile1081
  antroquinonol Drug Profile1092
  ATH-04 Drug Profile1111
  ATH-06 Drug Profile1121
  bempedoic acid Drug Profile11310
  BSN-272 Drug Profile1231
  CAT-2000 Series Drug Profile1241
  CAT-2003 Drug Profile1253
  colestilan chloride Drug Profile1281
  D-4F Drug Profile1291
  DCRPCSK-9 Drug Profile1301
  Drugs for Hypercholesterolemia Drug Profile1311
  Drugs to Inhibit Sortilin for Hypercholesterolemia Drug Profile1321
  DW-0929 Drug Profile1331
  DW-3102 Drug Profile1341
  DYB-186 Drug Profile1351
  EP-80317 Drug Profile1361
  evinacumab Drug Profile1372
  gemcabene calcium Drug Profile1392
  Gene Therapy to Inhibit PCSK9 for Hypercholesterolemia Drug Profile1411
  HCP-1305 Drug Profile1421
  HGP-0816 Drug Profile1431
  HS-25 Drug Profile1441
  inclisiran Drug Profile1454
  IONIS-ANGPTL3LRx Drug Profile1491
  IR-1002 Drug Profile1501
  KD-026 Drug Profile1511
  MBX-8025 Drug Profile1523
  MGL-3196 Drug Profile1552
  MGL-3745 Drug Profile1571
  MN-002 Drug Profile1581
  Monoclonal Antibodies to Inhibit PCSK9 for Hypercholesterolemia Drug Profile1591
  Monoclonal Antibody to Inhibit PCSK9 for Hypercholesterolemia Drug Profile1601
  PF-06446846 Drug Profile1611
  Recombinant Protein to Inhibit PCSK9 for Hypercholesterolemia Drug Profile1621
  RGX-501 Drug Profile1632
  rosuvastatin calcium Drug Profile1651
  Small Molecule for Hypercholesterolemia Drug Profile1661
  Small Molecule to Inhibit Endothelial Lipase for Hypercholesterolemia Drug Profile1671
  Small Molecule to Inhibit PCSK9 for Hypercholesterolemia Drug Profile1681
  Small Molecule to Inhibit PCSK9 for Hypercholesterolemia Drug Profile1691
  Small Molecules to Inhibit IDOL for Hypercholesterolemia Drug Profile1701
  Small Molecules to Inhibit PCSK9 for Hypercholesterolemia Drug Profile1711
  Small Molecules to Target O2 Radical and HMGCR for Ophthalmology, Cardiovascular, CNS and Metabolic Disorders Drug Profile1722
  ST-0702 Drug Profile1741
  SX-PCK9 Drug Profile1751
  Synthetic Peptide to Inhibit PCSK9 for Hypercholesterolemia Drug Profile1761
  Vaccine to Target PCSK9 for Hypercholesterolemia Drug Profile1771
  VK-2809 Drug Profile1783
  volanesorsen sodium Drug Profile1816
Hypercholesterolemia Dormant Projects1877
Hypercholesterolemia Discontinued Products1942
Hypercholesterolemia Product Development Milestones19617
  Featured News &Press Releases1961
    Nov 15, 2016: The Medicines Company and Alnylam Pharmaceuticals Present Positive Results from ORION-1 Phase 2 Study of Inclisiran (formerly PCSK9si)1961
    Nov 15, 2016: Viking Therapeutics Presents New Clinical Data on VK2809 in Subjects with Elevated Cholesterol at American Heart Association Scientific Sessions 20161971
    Nov 11, 2016: Regeneron and Sanofi to Present Data from Phase 3 Praluent (alirocumab) Injection Clinical Trials at AHA Scientific Sessions 20161982
    Oct 18, 2016: The Medicines Company Announces Positive Top-Line Results from Day 90 Interim Analysis in Ongoing ORION-1 Phase 2 Study of PCSK9si2001
    Oct 13, 2016: Bempedoic Acid Global Phase 3 Clinical Program to Include Patients on Any Statin at Any Dose2012
    Oct 05, 2016: The Medicines Company Provides Progress Update on Ongoing ORION-1 Study of PCSK9si2031
    Oct 04, 2016: Viking Therapeutics Doses First Patient in Phase 2 Clinical Trial of VK2809 in Patients with Hypercholesterolemia and Non-Alcoholic Fatty Liver Disease2041
    Sep 26, 2016: Gemphire Therapeutics Enrolls First Patient in the COBALT-1 Trial Investigating Gemcabene in Homozygous Familial Hypercholesterolemia2051
    Sep 19, 2016: Gemphire Therapeutics Announces Publication of Phase 2 Data for Gemcabene in the Journal of Clinical Lipidology2051
    Sep 15, 2016: Akcea Therapeutics Announces Presentations of New Data Underscoring Burden of Disease in Familial Chylomicronemia Syndrome2061
    Aug 30, 2016: The Medicines Company Provides Update on PCSK9si (PCSK9 synthesis inhibitor)2071
    Aug 29, 2016: Regeneron and Sanofi Present Positive Phase 3 Investigational Data for Praluent (alirocumab) Injection in Patients Undergoing LDL Apheresis Therapy at ESC Congress 20162081
    Aug 04, 2016: Esperion Therapeutics Provides Bempedoic Acid Development Program Update2091
    Jul 28, 2016: Akcea Therapeutics Receives Orphan Designation in Europe for Volanesorsen for the Treatment of Familial Partial Lipodystrophy2101
    Jul 05, 2016: Regeneron and Sanofi Announce Approval of Praluent (alirocumab) for the Treatment of Hypercholesterolemia in Japan2112
Appendix2132
  Methodology2131
  Coverage2131
  Secondary Research2131
  Primary Research2131
  Expert Panel Validation2131
  Contact Us2131
  Disclaimer2141

Table Of Contents

Global Markets Direct - Market Research—Global Markets Direct is a leading provider of global business intelligence and market analysis. It publishes a range of high quality market reports created by its large research and analysis capability and drawing from its extensive unique databases of industry-specific information.

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MLA:
Global Markets Direct - Market Research. "Hypercholesterolemia - Pipeline Review, H2 2016" Nov 23, 2016. Alacra Store. Apr 19, 2024. <http://www.alacrastore.com/storecontent/Global-Markets-Direct-Market-Research/Hypercholesterolemia-Pipeline-Review-H2-2016-2088-16872>
  
APA:
Global Markets Direct - Market Research. (2016). Hypercholesterolemia - Pipeline Review, H2 2016 Nov 23, 2016. New York, NY: Alacra Store. Retrieved Apr 19, 2024 from <http://www.alacrastore.com/storecontent/Global-Markets-Direct-Market-Research/Hypercholesterolemia-Pipeline-Review-H2-2016-2088-16872>
  
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