Alpha- Antitrypsin Deficiency - Pipeline Review, H2 2016 - Global Markets Direct - Market Research

Alpha- Antitrypsin Deficiency - Pipeline Review, H2 2016

Alpha- Antitrypsin Deficiency - Pipeline Review, H2 2016 - Global Markets Direct - Market Research
Alpha- Antitrypsin Deficiency - Pipeline Review, H2 2016
Published Aug 31, 2016
95 pages — Published Aug 31, 2016
Price US$ 2,000.00  |  Buy this Report Now

About This Report

  
Abstract:

Summary

Global Markets Directs, Alpha- Antitrypsin Deficiency - Pipeline Review, H2 2016, provides an overview of the Alpha- Antitrypsin Deficiency pipeline landscape.

The report provides comprehensive information on the therapeutics under development for Alpha- Antitrypsin Deficiency, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The report also covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases. Additionally, the report provides an overview of key players involved in therapeutic development for Alpha- Antitrypsin Deficiency and features dormant and discontinued projects.

Global Markets Directs report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Directs proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Drug profiles featured in the report undergoes periodic review following a stringent set of processes to ensure that all the profiles are updated with the latest set of information. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

The report helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data.

Scope

- The report provides a snapshot of the global therapeutic landscape of Alpha- Antitrypsin Deficiency
- The report reviews pipeline therapeutics for Alpha- Antitrypsin Deficiency by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved Alpha- Antitrypsin Deficiency therapeutics and enlists all their major and minor projects
- The report assesses Alpha- Antitrypsin Deficiency therapeutics based on drug target, mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news related to pipeline therapeutics for Alpha- Antitrypsin Deficiency

Reasons to buy

- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand important and diverse types of therapeutics under development for Alpha- Antitrypsin Deficiency
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and its most promising pipeline therapeutics
- Devis

  
Source:
Document ID
GMDHC8435IDB
Industry
Format:
PDF Adobe Acrobat
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Sections

TitleStarting PageNumber of Pages
Table of Contents26
  List of Tables61
  List of Figures71
Introduction81
  Global Markets Direct Report Coverage81
Alpha- Antitrypsin Deficiency Overview91
Therapeutics Development101
  Pipeline Products for Alpha- Antitrypsin Deficiency Overview101
Alpha- Antitrypsin Deficiency Therapeutics under Development by Companies112
Alpha- Antitrypsin Deficiency Pipeline Products Glance133
  Late Stage Products131
  Clinical Stage Products141
  Early Stage Products151
Alpha- Antitrypsin Deficiency Products under Development by Companies162
Alpha- Antitrypsin Deficiency Companies Involved in Therapeutics Development1819
  Adverum Biotechnologies, Inc.181
  Alnylam Pharmaceuticals, Inc.191
  Applied Genetic Technologies Corporation201
  Arrowhead Pharmaceuticals, Inc.211
  Carolus Therapeutics, Inc.221
  Cevec Pharmaceuticals GmbH231
  Dicerna Pharmaceuticals, Inc.241
  Digna Biotech, S.L.251
  Editas Medicine, Inc.261
  Grifols, S.A.271
  Inhibrx281
  Intellia Therapeutics, Inc.291
  International Stem Cell Corporation301
  Ionis Pharmaceuticals, Inc.311
  Kamada Ltd.321
  Polyphor Ltd.331
  ProMetic Life Sciences Inc.341
  rEVO Biologics, Inc.351
  Sangamo BioSciences, Inc.361
Alpha- Antitrypsin Deficiency Therapeutics Assessment379
  Assessment by Monotherapy Products371
  Assessment by Target382
  Assessment by Mechanism of Action402
  Assessment by Route of Administration422
  Assessment by Molecule Type442
Drug Profiles4632
  ALN-AAT Drug Profile463
  alpha-1 proteinase inhibitor (human) Drug Profile491
  alpha-1 proteinase inhibitor (human) second generation Drug Profile503
  ANN-001 Drug Profile532
  ARC-AAT Drug Profile553
  CT-2009 Drug Profile581
  DB-027 Drug Profile591
  Drugs for Alpha-1 Antitrypsin Deficiency Drug Profile601
  Gene Therapy to Activate Alpha-1 Antitrypsin for Alpha-Antitrypsin Deficiency Drug Profile612
  Gene Therapy to Activate Alpha-1 Antitrypsin for Alpha-Antitrypsin Deficiency Drug Profile631
  ISIS-AATRx Drug Profile641
  Oligonucleotides to Activate Alpha-1 Antitrypsin for Alpha-Antitrypsin Deficiency Drug Profile651
  Oligonucleotides to Inhibit Alpha-1 Antitrypsin for Alpha-Antitrypsin Deficiency Drug Profile661
  POL-6014 Drug Profile672
  rAAV2-CB-hAAT Drug Profile691
  Recombinant A1PI Drug Profile702
  Recombinant Human Alpha-1 Antitrypsin Drug Profile721
  Recombinant Human Alpha-1 Antitrypsin Replacement for Alpha-Antitrypsin Deficiency Drug Profile731
  Recombinant Protein for Alpha-1 Antitrypsin Deficiency Drug Profile741
  RNAi Oligonucleotide for Alpha-1 Antitrypsin Deficiency and Liver Disease Drug Profile752
  Stem Cell Therapy for Alpha-Antitrypsin Deficiency and Crigler-Najjar Syndrome Drug Profile771
Alpha- Antitrypsin Deficiency Dormant Projects781
Alpha- Antitrypsin Deficiency Discontinued Products791
Alpha- Antitrypsin Deficiency Product Development Milestones8014
  Featured News &Press Releases801
    May 11, 2016: Dicerna Reports Potent Preclinical Activity with GalNAc-DsiRNA-EX Conjugates801
    May 05, 2016: Investigational Gene-Based Therapy for Alpha-1 Antitrypsin Deficiency Demonstrates Durable Response at Five Years811
    Feb 25, 2016: Dicerna Reports Progress with GalNAc-DsiRNA-EX-Conjugates811
    Jan 20, 2016: AGTC Announces Data Evaluating Novel AAV-Based Gene Therapy as a Potential Treatment for Alpha-1 Antitrypsin Deficiency821
    Jan 19, 2016: Arrowhead's ARC-AAT Granted EMA Orphan Drug Designation831
    Dec 08, 2015: Kamada Completes Enrollment of U.S. Phase 2 Study of Inhaled Alpha-1 Antitrypsin for the Treatment of AAT Deficiency831
    Nov 09, 2015: Sangamo BioSciences Announces Publication Of Improved Method For Efficient Targeted Integration In Hematopoietic Stem Cells And T-cells841
    Jul 08, 2015: Arrowhead Receives Regulatory Clearance for ARC-AAT Phase 1 in the United Kingdom and New Zealand851
    Jul 02, 2015: Arrowhead Initiates Dosing of ARC-AAT in Patients with Alpha-1 Antitrypsin Deficiency851
    Jun 10, 2015: Arrowhead Receives Orphan Drug Designation for ARC-AAT861
    May 20, 2015: Kamada Reports Updated Data from European Phase 2/3 Clinical Study of Inhaled Alpha-1 Antitrypsin to Treat AAT Deficiency862
    May 05, 2015: Arrowhead Completes Dosing Healthy Volunteers and Initiates Transition to Patients in Phase 1 Study of ARC-AAT881
    Apr 20, 2015: Kamada Reports Additional Data from European Phase 2/3 Clinical Study of Inhaled Alpha-1 Antitrypsin to Treat AAT Deficiency893
    Feb 23, 2015: Arrowhead Begins Phase 1 Trial of ARC-AAT for Treatment of Liver Disease Associated with Alpha-1 Antitrypsin Deficiency921
    Jan 07, 2015: Kamada Reports Encouraging Discussions with European Co-Rapporteurs Regarding European Filing for Inhaled Alpha-1 Antitrypsin to Treat AATD931
Appendix942
  Methodology941
  Coverage941
  Secondary Research941
  Primary Research941
  Expert Panel Validation941
  Contact Us941
  Disclaimer951

Table Of Contents

Global Markets Direct - Market Research—Global Markets Direct is a leading provider of global business intelligence and market analysis. It publishes a range of high quality market reports created by its large research and analysis capability and drawing from its extensive unique databases of industry-specific information.

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Cite this Report

  
MLA:
Global Markets Direct - Market Research. "Alpha- Antitrypsin Deficiency - Pipeline Review, H2 2016" Aug 31, 2016. Alacra Store. May 13, 2025. <http://www.alacrastore.com/storecontent/Global-Markets-Direct-Market-Research/Alpha-Antitrypsin-Deficiency-Pipeline-Review-H2-2016-2088-16518>
  
APA:
Global Markets Direct - Market Research. (2016). Alpha- Antitrypsin Deficiency - Pipeline Review, H2 2016 Aug 31, 2016. New York, NY: Alacra Store. Retrieved May 13, 2025 from <http://www.alacrastore.com/storecontent/Global-Markets-Direct-Market-Research/Alpha-Antitrypsin-Deficiency-Pipeline-Review-H2-2016-2088-16518>
  
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