Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth - GBI Research Reports

Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth

Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth - GBI Research Reports
Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth
Published Feb 07, 2014
101 pages — Published Feb 07, 2014
Price US$ 3,500.00  |  Buy this Report Now

About This Report

  
Abstract:

Summary

GBI Research has released its pharma report Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth. The systemic psoriasis market is forecast to grow substantially over the forecast period from $5.0 billion in 2013 to $10.4 billion in 2020, across the eight major markets. This growth will be driven by a rising treatment population and the continued uptake of biologics.

Biologics will continue to drive market growth despite leading brands Enbrel (etanercept), Humira (adalimumab) and Remicade (infliximab) losing patent protection in most of the major markets over the forecast period. Although the market will suffer revenue losses as a result of sales erosion from biosimilar competitors, this will be offset by the emergence of novel therapies. Most notably, these include monoclonal antibodies secukinumab, ixekizumab and brodalumab, which are currently being developed by Alcon (Novartis subsidiary), Eli Lilly and Amgen, respectively.

Scope

- An introduction to psoriasis, which includes symptoms, epidemiology, etiology, pathophysiology, diagnosis and treatment
- Analysis of the major systemic therapies in the current psoriasis marketed landscape
- Analysis of the pipeline for psoriasis, which includes a breakdown of pipeline molecules by phase of development, molecule type, molecular target and novelty. Psoriasis clinical trials are analyzed by size, duration and failure rates, and a comparative analysis of the most promising systemic pipeline molecules is also provided.
- Forecast projections for the systemic psoriasis market to 2020. Analysis is provided for the global market and each of the eight major markets. The forecast incorporates projected, low and high variance scenarios based on treatment usage patterns and annual therapy costs in each of the major markets.
- Analysis of strategic consolidations, including co-development and licensing deals, within the psoriasis indication

Reasons to buy

- Understand the current systemic psoriasis marketed products landscape and recognize the dominant therapeutic agents and pharmaceutical players involved
- Identify trends and developments within the psoriasis pipeline and consider how the future competitive environment will be impacted
- Consider market opportunities and potential risks by examining the psoriasis clinical trial landscape in relation to industry averages
- Observe projections for treatment usage patterns, annual therapy costs and market growth in the eight major markets and understand reasons for variance in projected patterns of growth in the eight major markets

  
Source:
Document ID
GBIHC322MR
Industry
Format:
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Sections

TitleStarting PageNumber of Pages
Table of Contents44
  List of Tables61
  List of Figures71
Introduction89
  Overview81
  Epidemiology91
  Etiology, Co-morbidities and Risk Factors101
    Genetics101
    Psoriatic Arthritis101
    Mental Health Disorders111
    Metabolic Syndrome, Smoking, Diet and Alcohol Consumption111
    Infections111
    K ebner Phenomenon121
    Other Immune-mediated Diseases121
  Pathophysiology121
  Diagnosis131
  Treatment Options131
    Pharmacological Therapies141
    Non-pharmacological Therapies151
    Combination and Rotational Therapies151
    Quality of Life Assessments161
  Summary161
Marketed Products1711
  Overview171
  Methotrexate-based Products171
  Sandimmune/Neoral (cyclosporine/modified cyclosporine) Novartis181
  Soriatane (acitretin) Steifel Laboratories191
  Fumaderm (dimethyl fumarate and ethyl fumarate) Biogen Idec201
  Humira (adalimumab) Abbvie Inc.211
  Enbrel (etanercept) Amgen Inc.221
  Remicade (infliximab) Janssen Biotech231
  Stelara (ustekinumab) Janssen Biotech241
  Marketed Products Heat Map253
Pipeline2825
  Overview281
  Pipeline Size and Distribution by Phase, Molecule Type and Program Type292
  Pipeline Distribution by Molecular Target312
  Clinical Trial Landscape331
    Clinical Trial Duration334
    Clinical Trial Size374
  Clinical trial failure rates411
  Primary and Secondary Endpoints422
  Summary of Psoriasis Clinical Trials441
  Promising pipeline molecules441
    Ixekizumab Eli Lilly441
    Xeljanz (tofacitinib) Pfizer451
    Brodalumab Amgen461
    Apremilast Celgene471
    Secukinumab Alcon481
  Heat Map for Pipeline Products485
Market Forecast to 20205315
  Overview531
  Global Market533
  North America561
    Treatment Usage Patterns561
    Annual Cost of Treatment572
    Market Size591
  Top Five EU Markets601
    Treatment Usage Patterns601
    Annual Cost of Treatment611
    Market Size621
  Japan631
    Treatment Usage Patterns631
    Annual Cost of Treatment641
    Market Size651
  Drivers and Barriers for the Systemic Psoriasis Therapeutics Market661
    Drivers661
      Rising Global Prevalence661
      Changes in Patterns of Diagnosis and Treatment661
      Potential for Innovative Pipeline to Address Significant Unmet Need661
      High Cost of New Market Entries661
    Barriers661
      Use of Phototherapy661
      Loss of Patent Market Exclusivity for Leading Branded Biologics661
      Treatment Discontinuation and Limited Treatment Compliance671
Co-development and Licensing deals688
  Co-development Deals683
    Abbvie Enters into Co-development Agreement with Biotest for Tregalizumab711
    Lycera Enters into Research Agreement with Merck &Co.711
    LEO Pharma Enters into Research Agreement with 4SC Discovery for Inflammatory Skin Diseases711
    Amgen Enters into Co-Development Agreement with AstraZeneca for Five Human Monoclonal Antibodies Including Brodalumab712
  Licensing Deals732
    Leo Pharma Enters into Licensing Agreement with Virobay for Psoriasis Drug751
    Foamix Enters into Licensing Agreement with Dr. Reddy's Labs751
    Cipher Pharma Enters into Licensing Agreement with IBSA Institut Biochimique for Betesil Patch751
    Phenex Pharma Enters into Licensing Agreement with Janssen Biotech for Retinoid-Acid Receptor-Related Orphan Receptor Gamma t Program751
Appendix7626
  All Pipeline Drugs by Phase7612
    Discovery762
    Preclinical784
    Phase I822
    Phase II842
    Phase III861
    Undisclosed871
  Market Forecasts to 2020875
    Major Developed Markets871
    US881
    UK881
    France891
    Germany891
    Italy901
    Spain901
    Japan911
    Canada911
  Abbreviations921
  References935
  References for Heat Maps982
    Marketed Products981
    Pipeline products982
  Methodology1001
    Secondary Research1001
    Therapeutic Landscape1001
  Contact Us1001
  Disclaimer1011

Table Of Contents

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Cite this Report

  
MLA:
GBI Research Reports. "Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth" Feb 07, 2014. Alacra Store. May 04, 2025. <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Systemic-Psoriasis-Therapeutics-in-Major-Developed-Markets-to-2020-Continued-Uptake-of-Biologics-and-Novel-Pipeline-Drugs-to-Drive-Growth-2115-631>
  
APA:
GBI Research Reports. (2014). Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth Feb 07, 2014. New York, NY: Alacra Store. Retrieved May 04, 2025 from <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Systemic-Psoriasis-Therapeutics-in-Major-Developed-Markets-to-2020-Continued-Uptake-of-Biologics-and-Novel-Pipeline-Drugs-to-Drive-Growth-2115-631>
  
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