Re-evaluating Pharmaceutical Pipelines - Emerging Markets, Biologics and Orphan Drugs to Shape Future Decision Making - GBI Research Reports

Re-evaluating Pharmaceutical Pipelines - Emerging Markets, Biologics and Orphan Drugs to Shape Future Decision Making

Re-evaluating Pharmaceutical Pipelines - Emerging Markets, Biologics and Orphan Drugs to Shape Future Decision Making - GBI Research Reports
Re-evaluating Pharmaceutical Pipelines - Emerging Markets, Biologics and Orphan Drugs to Shape Future Decision Making
Published Jun 12, 2012
120 pages — Published Jun 12, 2012
Price US$ 3,500.00  |  Buy this Report Now

About This Report

  
Abstract:

Summary

GBI Research, a leading business intelligence provider, has released its latest research, Re-evaluating Pharmaceutical Pipelines - Emerging Markets, Biologics and Orphan Drugs to Shape Future Decision Making, which examines the key issues influencing the re-evaluation of pharmaceutical pipelines due to changes in the economic environment, the emergence of new markets, M&A and partnering activity, and recent advances in science and technology. It discusses the strategies the industry has adopted to address both internal and external challenges through open innovation, strategic acquisitions, partnerships and licensing deals.

GBI Researchs analysis highlights the trends in pharma productivity, the impact of drug attrition rates on different drug therapies, and the routes taken by companies to improve R&D efficiencies and maximize their product lifecycle management to ensure future growth and shareholder value.

It has been estimated that more than half of the products currently in late stage clinical development in pharmaceutical companies were originally derived from external sources. However, as the pool of innovative biotech and start-up companies contracts due to lack of venture capitalist funding, where will Pharma turn next? Find out more about the ways in which pharma is re-evaluating its product pipelines to invest in the future.

Scope

- Data and analysis regarding novel approaches to de-risk product development and address the shift in the geographical and therapeutic demands due to pharmerging markets and the changes in healthcare reform.
- Market analysis of R&D trends, identifying key areas of drug attrition and the strategies to reduce drug attrition and optimize product lifecycle management, including the expansion into OTC medicines, generics and biosimilars.
- Key challenges and opportunities that have had a significant impact on the market regarding geographical and therapeutic diversification of leading pharmaceutical companies.
- Key M&A activities and partnerships refueling company pipelines, including strategic acquisitions, collaborations, licensing deals, PPPs, CRADA s, JVs and risk sharing models.
- The competitive landscape and pharma R&D growth strategies adopted by leading pharmaceutical companies, including Johnson & Johnson, Merck & Co., Pfizer, Roche Group and Novartis.

Reasons to buy

- Identify the key market opportunities and align R&D portfolios to maximize growth
- Develop business strategies to optimize strategic acquisitions, collaborations and partnerships and licensing deals
- Devise a more tailored R&D approach to address specific geographical and therapeutic demands
- Develop key strategic initiatives by understanding the key factors impacting pharma R&D and preventing late stage product failures
- Re-evaluate and reassess investment decisions and explore ways in which to diversify and de-risk product development.

  
Source:
Document ID
GBIHC233MR
Industry
Format:
PDF Adobe Acrobat
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Sections

TitleStarting PageNumber of Pages
Table of Contents65
  List of Tables81
  List of Figures92
Introduction1116
  Market Conditions111
  Emerging Markets121
    Brazil121
    Russia121
    India121
    China131
  Healthcare Reform141
    The US141
    European Austerity151
  M&A and Partnerships161
    M&A Activity162
    Partnership Activity182
    Trends in 2011202
  Adopting New Business Models221
    Open Innovation Business Models231
  Advances in Science and Technology241
    Preclinical241
      Biomarkers241
    Clinical251
      Micro-Dosing Studies251
      Adaptive Clinical Trials261
R&D Trends2714
  Introduction271
    Drug Attrition vs. Therapy283
    Drug Attrition vs. Business Strategy312
    Strategies to Reduce Failure Rates in Phase III331
      Preventing Late Stage Failures due to PK/Bioavailability341
      Preventing Late Stage Failures Due to Toxicology351
      Preventing Late Stage Failures Due to Lack of Efficacy351
    Other Strategies to Reduce Drug Attrition351
  Maximizing Product Portfolios361
    New Uses for Existing Therapeutic Classes373
  Conclusions401
R&D Challenges and Opportunities4123
  Introduction411
  Geographical Diversification423
  Therapeutic Diversification451
    Biologics452
    Vaccines474
    Orphan Drugs517
  Generics and Biosimilars582
  OTC Medicines602
  Business Diversification621
    Animal Health621
    Consumer Healthcare621
    Diagnostics621
    Ophthalmic621
    Medical Devices621
  Conclusions631
Mergers, Acquistions and Partnerships - Refuelling Pipelines6412
  Mergers641
  Strategic Acquisitions651
    Acquisitions through Equity Stakes651
    Strategic Acquisitions in the New Market Segments652
    Strategic Acquisitions in the Therapeutic Areas671
  Collaborations and Partnerships671
    Collaborations682
    Licensing Deals701
    Public-Private Partnerships712
    Cooperative Research and Development Agreements731
    Joint Ventures741
    Risk Sharing Models751
  Conclusion751
Company Anaylsis7638
  Johnson &Johnson771
    Pharmaceuticals784
    Pharma R&D Growth Strategies821
    Divestments831
    Summary831
  Merck &Co.841
    Pharmaceuticals853
    Strategic Acquisitions and Partnerships881
    Pharma R&D Growth Strategies892
    Summary911
  Pfizer922
    Biopharmaceuticals943
    Strategic Acquisitions and Partnerships971
    Pharma R&D Growth Strategies982
    Summary1001
  Roche Group1002
    Pharmaceuticals1021
    Pharma R&D Growth Strategies1033
    Personalized Healthcare1061
    Summary1071
  Novartis1081
    Pharmaceuticals1093
    Pharma R&D Strategy1121
    Alcon Division1131
    Summary1131
Market Outlook1142
  Re-evaluation1141
    Investing for the Future1141
    Conflicts in the Business Model1151
    Cost-Effectiveness of Drugs1151
Appendix1165
  Market Definition1161
  Abbreviations1161
  Sources1172
  Methodology1192
    Primary Research1191
    Secondary Research1201
  Contacts Us1201
  Disclaimer1201

Table Of Contents

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Cite this Report

  
MLA:
GBI Research Reports. "Re-evaluating Pharmaceutical Pipelines - Emerging Markets, Biologics and Orphan Drugs to Shape Future Decision Making" Jun 12, 2012. Alacra Store. May 05, 2025. <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Re-evaluating-Pharmaceutical-Pipelines-Emerging-Markets-Biologics-and-Orphan-Drugs-to-Shape-Future-Decision-Making-2115-436>
  
APA:
GBI Research Reports. (2012). Re-evaluating Pharmaceutical Pipelines - Emerging Markets, Biologics and Orphan Drugs to Shape Future Decision Making Jun 12, 2012. New York, NY: Alacra Store. Retrieved May 05, 2025 from <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Re-evaluating-Pharmaceutical-Pipelines-Emerging-Markets-Biologics-and-Orphan-Drugs-to-Shape-Future-Decision-Making-2115-436>
  
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