Orphan Diseases Therapeutics in CNS to 2017 - Novel Agents such as AMR101 and ACR16 to Provide Treatment Options and Boost the Huntingtons Disease Segment - GBI Research Reports

Orphan Diseases Therapeutics in CNS to 2017 - Novel Agents such as AMR101 and ACR16 to Provide Treatment Options and Boost the Huntingtons Disease Segment

Orphan Diseases Therapeutics in CNS to 2017 - Novel Agents such as AMR101 and ACR16 to Provide Treatment Options and Boost the Huntingtons Disease Segment - GBI Research Reports
Orphan Diseases Therapeutics in CNS to 2017 - Novel Agents such as AMR101 and ACR16 to Provide Treatment Options and Boost the Huntingtons Disease Segment
Published Apr 02, 2012
124 pages — Published Apr 02, 2012
Price US$ 3,500.00  |  Buy this Report Now

About This Report

  
Abstract:

Summary

GBI Research, the leading business intelligence provider, has released its latest research Orphan Diseases Therapeutics in CNS to 2017 - Novel Agents such as AMR101 and ACR16 to Provide Treatment Options and Boost the Huntingtons Disease Segment, which provides insights into the CNS orphan disease therapeutics market until 2017. The report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GBI Researchs team of industry experts. The report provides an in-depth analysis of amyotrophic lateral sclerosis, huntingtons disease and myasthenia gravis. It also provides the share of generics in global CNS orphan disease therapeutics and in each indication market. The report examines the global orphan diseases therapeutics in CNS usage patterns. It includes the geographical distribution of amyotrophic lateral sclerosis, huntingtons disease and myasthenia gravis markets across the US, the top five countries of Europe and in Japan. The report also includes insights into the orphan diseases therapeutics in CNS Research and Development (R&D) product pipeline and explores the competitive landscape, including major players in the CNS orphan disease therapeutics market. Finally, the report includes analysis on Mergers and Acquisitions (M&A) and licensing agreements that took place in the orphan diseases therapeutics in CNS market.

GBI Researchs analysis shows that the overall global CNS orphan disease market is set to increase over the forecast period. It grew from $359.6m in 2002 to $665.5m in 2010 at a Compound Annual Growth Rate (CAGR) of 8%. This is projected to increase to a CAGR of 17.6% over the forecast period to $2.1 billion in 2017. The global ALS therapeutics market generated approximately $163.2m in 2010, growing from $109.7m in 2002 at a CAGR of 5.1%. By 2017, this is expected to have increased to $210.5m at a CAGR of 3.7%. ALS was one of the biggest orphan CNS disease markets globally in 2010. The global HD therapeutics market generated approximately $126.7m in 2010, growing from $34.3m in 2002 at a CAGR of 17.8%. By 2017, this is expected to have increased to $786.5m at a CAGR of 29.8%. Globally, the MG therapeutics market increased from $42.5m in 2002 to $57.7m in 2010 at a CAGR of 3.9%. Over the forecast period it is expected to grow to $88.6m in 2017 with a higher CAGR of 6.3%.

Scope

- The report analyzes treatment usage patterns, market characterization, pipeline analysis, competitive landscape and key M&A trends in the global orphan diseases therapeutics in CNS market for three indications, amyotrophic lateral sclerosis, huntingtons disease and myasthenia gravis.
- Data and analysis on the orphan diseases therapeutics in CNS market in the leading geographies of the world the US, the UK, Germany, France, Italy, Spain and Japan.
- Annualized market data for the orphan diseases therapeutics in CNS market from 2004 to 2010, with forecasts to 2017.
- Market data on the geographical landscape and therapeutic landscape, including market size, market share, annual cost of therapy, sales volume and treatment usage patterns such as disease population, treatment seeking population, diagnosis population and prescription population.
- Share of the generics in global orphan diseases therapeutics in CNS market and for the market of each indication that is covered in the report.
- Key drivers and restraints that have had a significant impact on the market.
- The competitive landscape of the global market including top companies benchmarking. The key companies studied in this report are Biogen Idec, Avanir Pharmaceuticals, Neuraltus Pharmaceuticals, Cytokinetics, The Avicena Group, NeuroSearch, Trophos, Amarin Corporation, Siena Biotech, Sanofi.
- Key M&A activities and licensing agreements

  
Source:
Document ID
GBIHC144MR
Industry
Format:
PDF Adobe Acrobat
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Sections

TitleStarting PageNumber of Pages
Table of Contents36
  List of Tables52
  List of Figures72
Orphan Diseases Therapeutics in CNS - Introduction92
  GBI Research Report Guidance101
Orphan Diseases Therapeutics in CNS - Market Overview1112
  Introduction111
  Orphan Disease Regulation and Incentives112
  Global Revenue Forecasts for Orphan Diseases Therapeutics in CNS131
    Global Revenue and Forecast132
    Geographical Segmentation152
    Branded and Generic Market Share171
    Revenue Share by Indication182
    Market Drivers201
      Regulatory Incentives will Encourage R&D201
      Targeting Non-Orphan Indications with Orphan Drugs Increases Market Potential for Orphan Drugs201
      Generic Drugs are not a Threat to Disease-Modifying Therapies211
    Market Restraints211
      Conducting Clinical Trials for Orphan Diseases in the CNS is Difficult211
      CNS Diseases are Poorly Understood and this Hinders Drug Development211
    Unmet Needs211
    Opportunities221
Orphan Diseases Therapeutics in CNS - Geographical Landscape234
  The US231
    Revenue232
  Top Five Countries of Europe251
    Revenue251
  Japan261
    Revenue261
Orphan Diseases in CNS Disorders - Therapeutic Landscape2744
  Amyotrophic Lateral Sclerosis271
    Disease Overview271
    Revenue274
    Average Annual Cost of Treatment312
    Branded and Generic Market Share331
    Treatment Algorithm341
    Treatment Usage Patterns341
      Diseased Population342
      Treatment Seeking Population362
      Diagnosed Population382
      Prescription Population401
    Approved Molecules411
    Rilutek411
      Mechanism of Action411
      Efficacy Details411
      Safety Profile411
      Cost of Therapy421
    Nuedexta (Dextromethorphan Hydrobromide and Quinidine Sulfate)421
      Mechanism of Action421
      Efficacy421
      Safety421
      Cost of Therapy431
  Huntington s Disease431
    Disease Overview431
    Total Revenue443
    Average Annual Cost of Treatment (ACT)471
    Branded and Generic Market Share481
    Treatment Algorithm491
    Treatment Usage Patterns501
      Diseased Population501
      Treatment Seeking Population511
      Diagnosed Population521
      Prescription Population531
  Approved Molecules541
    Xenazine (tetrabenazine)541
      Mechanism of Action541
      Efficacy Details541
      Safety Profile541
      Cost of Therapy551
  Myasthenia Gravis551
    Disease Overview551
    Total Revenue563
    Branded and Generic Market Share591
    Average Annual Cost of Treatment601
    Treatment Algorithm611
    Treatment Usage Patterns621
      Diseased Population621
      Treatment Seeking Population631
      Diagnosed Population641
      Prescription Population651
    Approved Molecules661
      Prograf (Tacrolimus)661
  Other Indications671
    Total Revenue671
    Product Profiles681
      Apokyn (Apomorphine Hydrochloride)681
      Diacomit (Stiripentol)681
      Banzel (Rufinamide)691
      Lamictal (Lamotrigine)691
      Modafinil701
      Prialt (Ziconotide Intrathecal Infusion)701
Global Orphan Diseases in CNS Disorders - Pipeline Analysis7114
  Introduction711
  Research and Development Pipeline721
    Overview723
    Pipeline by Clinical Phases of Development751
      Discovery751
      Pre-clinical762
      IND Filed781
      Phase I791
      Phase II801
      Phase III811
    Profiles of Promising Drugs in Orphan Diseases in CNS Disorders821
      CK-2017357821
      Dexpramipexole821
      NP001821
      TRO19622 (Olesoxime)821
      Huntexil831
      AMR 101831
      HD-02831
      SEN196831
      Venoglobulin-IH831
      Revimmune841
      Soliris (Eculizumab)841
Global Orphan Diseases in CNS Disorders - Competitive Landscape8510
  Major Players851
  Major Company Profiles851
    Biogen Idec851
      SWOT Analysis851
    Avanir861
      SWOT Analysis861
    Neuraltus871
      SWOT Analysis871
    Cytokinetics881
      SWOT Analysis881
    Avicena891
      SWOT Analysis891
    NeuroSearch901
      SWOT Analysis901
    Trophos911
      SWOT Analysis911
    Amarin921
      SWOT Analysis921
    Siena Biotech931
      SWOT Analysis931
    Sanofi941
      SWOT Analysis941
Global Orphan Diseases in CNS Disorders - Strategic Consolidations9521
  Mergers and Acquisitions951
    Overview952
    Major Mergers and Acquisitions Deals971
      H. Lundbeck Acquires LifeHealth971
      H. Lundbeck Acquires OVATION Pharmaceuticals971
      CytRx Acquires Clinical and Pharmaceutical Assets from Biorex971
      Pfizer Acquires FoldRx Pharmaceuticals971
    Segmentation by Indication981
    Segmentation by Geography991
    Segmentation by Deal Value1001
    Segmentation by Year1011
  Licensing Agreements1021
    Overview1023
    Major Licensing Deals1051
      NeuroSearch Terminates Licensing Agreement with Astellas Pharma for the Rights for ACR161051
      Biovail Acquires Rights for Tetrabenazine and Related Assets from Cambridge Laboratories1051
      Biogen Idec Enters into Licensing Agreement with Knopp Neurosciences for KNS-7607041061
      Brain Science Institute Enters into Licensing Agreement with Eisai1061
      Debiopharm Enters into Licensing Agreement with DeveloGen1061
      Amorfix Life Sciences Enters into Licensing Agreement with Biogen Idec1061
    Segmentation by Indication1071
    Segmentation by Geography1081
    Segmentation by Deal Value1091
    Segmentation by Year1101
  Co Development Deals1112
    Segmentation by Geography1131
    Segmentation by Value1141
    Segmentation by Year1151
CNS Orphan Diseases - Appendix1169
  Market Definition1161
  Abbreviations1161
  Research Methodology1172
    Coverage1181
    Secondary Research1181
    Primary Research1181
  Forecasting1192
    Epidemiology-based Forecasting1191
    Expert Panels Validation1201
  Contact Us1201
  Disclaimer1201
  Sources1205

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Cite this Report

  
MLA:
GBI Research Reports. "Orphan Diseases Therapeutics in CNS to 2017 - Novel Agents such as AMR101 and ACR16 to Provide Treatment Options and Boost the Huntingtons Disease Segment" Apr 02, 2012. Alacra Store. May 07, 2025. <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Orphan-Diseases-Therapeutics-in-CNS-to-2017-Novel-Agents-such-as-AMR101-and-ACR16-to-Provide-Treatment-Options-and-Boost-the-Huntingtons-Disease-Segment-2115-371>
  
APA:
GBI Research Reports. (2012). Orphan Diseases Therapeutics in CNS to 2017 - Novel Agents such as AMR101 and ACR16 to Provide Treatment Options and Boost the Huntingtons Disease Segment Apr 02, 2012. New York, NY: Alacra Store. Retrieved May 07, 2025 from <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Orphan-Diseases-Therapeutics-in-CNS-to-2017-Novel-Agents-such-as-AMR101-and-ACR16-to-Provide-Treatment-Options-and-Boost-the-Huntingtons-Disease-Segment-2115-371>
  
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