Sections
Title | Starting Page | Number of Pages |
---|
Table of Contents | 6 | 4 |
List of Tables | 8 | 1 |
List of Figures | 9 | 1 |
Macular Degeneration Asia-Pacific Market to 2019 Introduction | 10 | 18 |
Symptoms | 10 | 1 |
Etiology | 11 | 1 |
Pathophysiology | 11 | 1 |
Disease Initiation | 12 | 1 |
Disease Propagation | 12 | 1 |
Dry AMD | 12 | 1 |
Wet AMD | 12 | 2 |
Classification | 14 | 1 |
Early AMD | 14 | 1 |
Intermediate AMD | 14 | 1 |
Advanced AMD | 15 | 1 |
Geographic Atrophy | 15 | 1 |
Wet AMD | 15 | 1 |
Co-morbidities and Complications | 16 | 1 |
Diagnosis | 17 | 1 |
History | 17 | 1 |
Examination | 17 | 1 |
Amsler Grid | 17 | 1 |
Visual Acuity Testing | 18 | 1 |
Slit Lamp Microscopy | 18 | 1 |
Ophthalmoscopy | 18 | 1 |
Diagnostic Tests | 18 | 1 |
Fundus Fluorescein Angiography | 18 | 1 |
Indocyanine Green Angiography | 19 | 1 |
Ocular Coherence Tomography | 19 | 1 |
Fundus Photography | 19 | 1 |
Autofluorescence | 19 | 1 |
Epidemiology | 20 | 2 |
Prognosis and Disease Staging | 22 | 1 |
Treatment Options | 22 | 1 |
Pharmacological | 22 | 1 |
Anti-VEGF Agents | 22 | 1 |
Photodynamic Therapy | 23 | 1 |
Treatment Algorithms and Prescribing Habits | 24 | 2 |
Non-pharmacological Care | 26 | 1 |
Laser Photocoagulation | 26 | 1 |
Implantable Miniature Telescope | 26 | 1 |
Transpupillary Thermotherapy | 27 | 1 |
Surgical Therapy | 27 | 1 |
Macular Degeneration Asia-Pacific Market to 2019 Marketed Products | 28 | 9 |
Therapeutic Landscape | 29 | 1 |
Lucentis (ranibizumab) Novartis AG/Roche (Genentech) | 29 | 1 |
Eylea (aflibercept) Regeneron Pharmaceuticals/Bayer Healthcare | 30 | 2 |
Avastin (bevacizumab) Genentech (Roche) | 32 | 1 |
Macugen (pegaptanib sodium) Valeant Pharmaceuticals/Pfizer | 32 | 1 |
Visudyne (verteporfin injection) Novartis AG | 33 | 1 |
Triamcinolone Acetonide | 34 | 1 |
Comparative Efficacy and Safety | 35 | 2 |
Macular Degeneration Asia-Pacific Market to 2019 Pipeline for Disease | 37 | 11 |
Overall Pipeline | 37 | 2 |
Pipeline Analysis by Molecule Type | 39 | 2 |
Pipeline Analysis by Mechanism of Action | 41 | 2 |
Clinical Trials | 43 | 1 |
Failure Rate | 43 | 1 |
Clinical Trial Duration | 44 | 1 |
Clinical Trial Size | 45 | 1 |
Promising Drug Candidates in the Pipeline | 46 | 1 |
MC-1101 MacuCLEAR, Inc. | 46 | 1 |
KH902 (Fumintide) Chengdu Kanghong Pharmaceuticals Group Co., Ltd. | 46 | 2 |
Macular Degeneration Asia-Pacific Market to 2019 Market Forecast to 2019 | 48 | 12 |
Geographical Markets | 48 | 1 |
APAC Market | 48 | 1 |
Treatment Usage Patterns | 48 | 1 |
Annual Cost of Treatment | 48 | 1 |
Market Size | 48 | 2 |
Australia | 50 | 1 |
Treatment Usage Patterns | 50 | 1 |
Annual Cost of Treatment | 50 | 1 |
Market Size | 50 | 2 |
China | 52 | 1 |
Treatment Usage Patterns | 52 | 1 |
Annual Cost of Treatment | 52 | 1 |
Market Size | 52 | 2 |
India | 54 | 1 |
Treatment Usage Patterns | 54 | 1 |
Annual Cost of Treatment | 54 | 1 |
Market Size | 54 | 2 |
Japan | 56 | 1 |
Treatment Usage Patterns | 56 | 1 |
Annual Cost of Treatment | 56 | 1 |
Market Size | 56 | 2 |
Drivers and Barriers for the Disease Market | 58 | 1 |
Drivers | 58 | 1 |
Geriatric Population to Drive Macular Degeneration Market | 58 | 1 |
Strong Patent Protection of Dominant Drugs | 58 | 1 |
Improvement in Diagnostic Techniques and Increase in Awareness | 58 | 1 |
Barriers | 59 | 1 |
Off-label Use of Avastin Impacts Annual Cost of Therapy | 59 | 1 |
Poor Prescription Rates | 59 | 1 |
High Failure Rate in Late Stage Clinical Trials | 59 | 1 |
Macular Degeneration Asia-Pacific Market to 2019 Deals and Strategic Consolidations | 60 | 7 |
Deals Analysis | 60 | 2 |
Major Co-development Deals | 62 | 1 |
Sinphar Enters into Co-development Agreement with MacuCLEAR | 62 | 1 |
Allergan Enters into Co-development Agreement with Molecular Partners | 63 | 1 |
X-Body BioSciences Enters into Co-development Agreement with Hengrui Medicine for AMD | 63 | 1 |
Alcon Enters into Collaboration with AstraZeneca | 63 | 1 |
Acucela Enters into Co-Development Agreement with Otsuka Pharma for ACU-4429 | 63 | 1 |
Major Licensing Deals | 64 | 1 |
Allegro Ophthalmics Enters into Licensing Agreement with Senju Pharma to Develop Integrin Peptide Therapy | 65 | 1 |
Allergan Enters into Licensing Agreement with Molecular Partners | 65 | 1 |
PanOptica Enters into Licensing Agreement with OSI Pharma | 65 | 1 |
Lpath Enters into Licensing Agreement with Pfizer | 65 | 1 |
Shionogi Enters into Licensing Agreement with OncoTherapy Science | 66 | 1 |
Macular Degeneration Asia-Pacific Market to 2019 Appendix | 67 | 15 |
All Pipeline Drugs by Phase | 67 | 5 |
Discovery | 67 | 1 |
Preclinical | 68 | 1 |
IND-filed and Phase 0 | 69 | 1 |
Phase I | 69 | 1 |
Phase II | 70 | 1 |
Phase III | 70 | 1 |
Undisclosed | 71 | 1 |
Market Forecasts to 2019 | 71 | 2 |
Asia-Pacific | 71 | 1 |
Australia | 71 | 1 |
China | 72 | 1 |
India | 72 | 1 |
Japan | 72 | 1 |
Market Definitions | 73 | 1 |
Abbreviations | 73 | 2 |
References | 75 | 2 |
Research Methodology | 77 | 5 |
Coverage | 77 | 1 |
Secondary Research | 77 | 1 |
Primary Research | 77 | 1 |
Therapeutic Landscape | 78 | 1 |
Epidemiology-based Forecasting | 78 | 2 |
Market Size by Geography | 80 | 1 |
Geographical Landscape | 81 | 1 |
Pipeline Analysis | 81 | 1 |
Expert Panel Validation | 81 | 1 |
Contact Us | 81 | 1 |
Disclaimer | 81 | 1 |