Liver Cancer Therapeutics Market to 2018 - Nexavar, the Only Approved Targeted Therapy for Advanced Disease, Continues to Dominate as Other Late Stage Trials Fail - GBI Research Reports

Liver Cancer Therapeutics Market to 2018 - Nexavar, the Only Approved Targeted Therapy for Advanced Disease, Continues to Dominate as Other Late Stage Trials Fail

Liver Cancer Therapeutics Market to 2018 - Nexavar, the Only Approved Targeted Therapy for Advanced Disease, Continues to Dominate as Other Late Stage Trials Fail - GBI Research Reports
Liver Cancer Therapeutics Market to 2018 - Nexavar, the Only Approved Targeted Therapy for Advanced Disease, Continues to Dominate as Other Late Stage Trials Fail
Published Dec 31, 2012
72 pages — Published Dec 31, 2012
Price US$ 3,500.00  |  Buy this Report Now

About This Report

  
Abstract:

Summary

Leading business intelligence provider, GBI Research, has released its latest research report, entitled: Liver Cancer Therapeutics Market to 2018 - Nexavar, the Only Approved Targeted Therapy for Advanced Disease, Continues to Dominate as Other Late Stage Trials Fail. The report provides insights into the liver cancer therapeutics market in the US, the top five European countries (the UK, Germany, France, Italy and Spain) and Japan, with market forecasts until 2018. It provides in-depth analysis of the major marketed products, as well as insights into the liver cancer therapeutics R&D pipeline. The report also gives in-depth analysis of the unmet needs, drivers and barriers that affect the markets in these countries. Additionally, it discusses the global pipeline for all the liver cancer molecules across various stages of development.

The report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GBI Researchs team of industry experts.

GBI Research found that the liver cancer therapeutics in the top seven markets (the US, the UK, Germany, France, Spain, Italy and Japan) was estimated at $374.3m in 2011, having grown at a Compound Annual Growth Rate (CAGR) of 21.7% from 2004. Growth was driven by an increase in the patient volume and the Annual Cost of Therapy (ACT) per patient, which increased due to the approval of Nexavar (sorafenib) in the US and Europe. The market is forecast to reach revenues of $644.3m by 2018, growing at a CAGR of 8.1% from 2011.

The current competition in the liver cancer market is weak, as Nexavar is the only drug approved for advanced Hepatocellular Carcinoma (HCC) with the exception of Miripla (miriplatin) in Japan. However, there are some molecules in Phase III development as first-line and second-line treatments which promise to influence the competitive landscape in the next two to three years. The anticipated launch of Eli Lilly's ramucirumab (IMC-1121B), a monoclonal antibody in 2014; Celsion Corporation's ThermoDox in 2014; and PrevOnco in 2015 will drive the market forward.

Scope

- Annualized market data for the liver cancer therapeutics market from 2004 to 2011 and forecast to 2018
- Analysis of the liver cancer therapeutics market in the leading geographies of the world: the US, the UK, Germany, France, Italy, Spain, and Japan
- Market characterization of the liver cancer therapeutics market including market size, annual cost of therapy and treatment usage patterns
- Key drivers and barriers that affect the market
- Coverage of pipeline molecules in various Phases of drug development
- Competitive benchmarking of leading companies including Bayer and Dainippon Sumitomo Pharma
- Key M&A activities and licensing agreements that have taken place between 2008 and October 2012 in liver cancer therapeutics in the top seven markets

Reasons to buy

- Align your product portfolio to the markets with high growth potential
- Develop market-entry and market-expansion strategies by identifying the regions and market segments poised for strong growth
- Create a more tailored country strategy through the understanding of key drivers and barriers of the liver cancer therapeutics market
- Develop key strategic initiatives by understanding the key focus areas and top-selling products of leading companies
- Accelerate and strengthen your market position by identifying key companies for mergers, acquisitions and strategic partnerships

  
Source:
Document ID
GBIHC287MR
Industry
Format:
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Sections

TitleStarting PageNumber of Pages
Table of Contents54
  List of Tables71
  List of Figures81
Liver Cancer Therapeutics Market to 2018 - Introduction91
Liver Cancer Therapeutics Market to 2018 - Overview109
  Introduction101
    Benign Tumor101
      Hemangioma101
      Hepatic Adenoma101
      Focal Nodular Hyperplasia101
    Primary Liver Cancer101
      Hepatocellular Carcinoma101
      Intrahepatic Cholangiocarcinoma101
      Angiosarcomas and Hemangiosarcomas101
      Hepatoblastoma101
    Secondary Liver Cancer101
  Symptoms111
  Diagnosis111
    Laboratory Tests111
      Liver Function Tests111
      Alpha-fetoprotein Blood Test111
    Imaging Tests111
      Ultrasound111
      Computed Tomography Scan111
      Magnetic Resonance Imaging111
      Angiography121
      Bone Scan121
    Others121
      Biopsy121
      Laparoscopy121
  Treatment Options121
    Surgery131
      Resection131
      Liver Transplant131
    Non-surgical131
      Transarterial Chemoembolization131
      Intra-arterial Chemotherapy131
      Ablation Therapy131
      Radiation Therapy141
      Systemic Therapy141
      Chemotherapy141
      Targeted Therapy141
    General Treatment Algorithm151
    Treatment by Stage161
      Stages I and II (Localized)161
      Stage III and Stage IV (Regional and Distant)171
    New Technologies in Treatment181
      Radiation therapy181
      Targeted Therapy181
      Virus Therapy181
Liver Cancer Therapeutics Market to 2018 - Market Characterization and Forecasts1911
  Revenue193
  Annual Cost of Therapy221
  Marketed Products231
    Nexavar231
      Introduction231
      Mechanism of Action231
      Clinical Studies - Results from Sorafenib HCC Assessment Randomized Protocol (SHARP) Trial Study231
      Adverse Reactions241
      Approval History of Nexavar251
    Miripla251
      Introduction251
      Mechanism of Action251
      Clinical Studies251
      Safety261
      Approval History of Miripla261
  Treatment Usage Pattern271
    Prevalence Population281
    Diagnosed Population281
    Prescription Population281
  Drivers and Barriers of Liver Cancer Therapeutics Market281
    Drivers281
      High Incidence Rate281
      High Activity in Pipeline281
      High Unmet Need281
    Barriers291
      Poor Hepatocellular Carcinoma Prognosis291
      Affordability of High-cost Treatment291
      Lack of Medical Expertise for Early Diagnosis291
Liver Cancer Therapeutics Market to 2018 - Geographical Landscape3011
  US301
    Introduction301
    Revenue302
    Cost of Therapy321
    Treatment Usage Pattern331
  Top Five European Countries341
    Introduction341
    Revenue342
    Cost of Therapy361
    Treatment Usage Pattern371
  Japan381
    Introduction381
    Revenue381
    Cost of Therapy391
    Treatment Usage Pattern401
Liver Cancer Therapeutics Market to 2018 - Pipeline Analysis4110
  Introduction412
  R&D Product Pipeline by Stage of Development431
    Phase III431
    Phase II/III441
    Phase II441
    Phase I/II451
    Phase I461
    Pre-Clinical471
    Discovery471
  Profiles of Promising Molecules481
    PrevOnco481
      Product Description481
      Mechanism of Action481
      Clinical Study Details481
    Ramucirumab481
      Product Description481
      Mechanism of Action491
      Clinical Study Details491
    ThermoDox491
      Product Description491
      Mechanism of Action491
      Clinical Study Details491
    Afinitor501
      Product Description501
      Mechanism of Action501
      Clinical Study Details501
Liver Cancer Therapeutics Market to 2018 - Competitive Landscape512
  Bayer511
  Dainippon Sumitomo Pharma521
Liver Cancer Therapeutics Market to 2018 - Strategic Consolidations5311
  Introduction531
  Deals by Geography541
  Deals by Year551
  Mergers and Acquisition Deals561
    Overview561
    Profiles of Major M&A Deals571
      DNAtrix Merges with VectorLogics571
      GlaxoSmithKline Completes Acquisition of Human Genome Sciences for $3.6 Billion571
      North Horizon Completes Acquisition of FasTrack Pharma in Reverse Acquisition571
      Pharmascience Acquires Aegera Therapeutics571
      Myotec Therapeutics Merges with Hybrid BioSystems581
  Licensing Agreements581
    Overview582
    Profiles of Major Licensing Agreements601
      Astellas Pharma Enters into Licensing Agreement with AVEO Pharma for Tivozanib601
      Alnylam Pharma Enters into Licensing Agreement with Ascletis Pharma to Develop ALN-VSP601
      GE Healthcare Enters into Licensing Agreement with Dyax for c-Met Imaging Peptides611
      4SC Enters into Licensing Agreement with Yakult Honsha for Resminostat611
      Ono Pharma Enters into Licensing Agreement with OncoTherapy611
  Co-Development Agreements621
    Overview621
    Profiles of Major Co-Development Agreements631
      Beijing Genomics Institute Enters into Co-Development Agreement with Asia Cancer Research Group631
      Ludwig Institute Enters into Co-Development Agreement with Polaris for ADI-PEG 20631
      Pfizer Enters into an Agreement with Samsung Medical Center631
      Indivumed Expands Collaboration with Georgetown University631
Liver Cancer Therapeutics Market to 2018 - Appendix649
  Market Definitions641
  Abbreviations642
  Bibliography661
  Research Methodology672
    Coverage671
    Secondary Research681
    Primary Research681
  Therapeutic Landscape692
    Epidemiology-Based Forecasting691
    Market Size by Geography701
  Geographical Landscape711
  Pipeline Analysis711
  Competitive Landscape721
    Expert Panel Validation721
  Contact Us721
  Disclaimer721

Table Of Contents

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Cite this Report

  
MLA:
GBI Research Reports. "Liver Cancer Therapeutics Market to 2018 - Nexavar, the Only Approved Targeted Therapy for Advanced Disease, Continues to Dominate as Other Late Stage Trials Fail" Dec 31, 2012. Alacra Store. May 04, 2025. <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Liver-Cancer-Therapeutics-Market-to-2018-Nexavar-the-Only-Approved-Targeted-Therapy-for-Advanced-Disease-Continues-to-Dominate-as-Other-Late-Stage-Trials-Fail-2115-549>
  
APA:
GBI Research Reports. (2012). Liver Cancer Therapeutics Market to 2018 - Nexavar, the Only Approved Targeted Therapy for Advanced Disease, Continues to Dominate as Other Late Stage Trials Fail Dec 31, 2012. New York, NY: Alacra Store. Retrieved May 04, 2025 from <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Liver-Cancer-Therapeutics-Market-to-2018-Nexavar-the-Only-Approved-Targeted-Therapy-for-Advanced-Disease-Continues-to-Dominate-as-Other-Late-Stage-Trials-Fail-2115-549>
  
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