Innovation in the Prefilled Syringe Market - Biologics and Autoinjection Devices Shaping Future R&D Trends - GBI Research Reports

Innovation in the Prefilled Syringe Market - Biologics and Autoinjection Devices Shaping Future R&D Trends

Innovation in the Prefilled Syringe Market - Biologics and Autoinjection Devices Shaping Future R&D Trends - GBI Research Reports
Innovation in the Prefilled Syringe Market - Biologics and Autoinjection Devices Shaping Future R&D Trends
Published Dec 14, 2012
28 pages — Published Dec 14, 2012
Price US$ 3,500.00  |  Buy this Report Now

About This Report

  
Abstract:

Summary

GBI Research, the leading business intelligence provider, has released its latest research, Innovation in the Prefilled Syringe Market - Biologics and Autoinjection Devices Shaping Future R&D Trends, which provides insights into possible future avenues of R&D in the prefilled syringe market. This includes an overview of problems and possible solutions, as well as discussion of how the devices have developed to date to address problems with contamination, safety, fragility and ease of use.

The report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GBI Researchs team of industry experts.

The market for prefilled syringes is being driven by the rise in popularity of autoinjection devices for the home-use market. As health authorities seek to reduce costs, facilitating patients in self-administering their medication is one major way of reducing the strain on resources for providers. Additionally, patients prefer this option as it does not require them to travel to hospital and can be accommodated in their own home.

Innovation is also being driven by safety. This area has seen increasing innovation in response to regulations and guidelines concerning needlestick injury. This is an area of rising concern as the number of logged needlestick injuries in healthcare workers is high and thought to be considerably under-reported. Measures to ensure healthcare provider safety have been put in place, and pharmaceutical companies are responding by improving the safety of their prefilled syringes in order to increase their appeal and gain market share. Safety devices have moved from active devices, which require activation by the user, to passive, which are automatically activated. The next steps are being made in integrating the safety device into the needle during manufacture.

The development of injectable biologic therapies is a major factor in the future prospects of prefilled syringes. Although oral biologics are something that companies are aiming for and there are some in development, many peptides are broken down too quickly in the stomach and are therefore not useful in treatment. The mainstay of biologic treatment is likely to remain injectable, whether intravenous, subcutaneous or intramuscular, for the foreseeable future. As such, companies need to overcome the limitations of prefilled syringes in order to provide convenient method of administration and win market share.

Scope

- An overview of issues in the market.
- Innovative solutions to these problems.
- Future developments expected in the market by leading players

Reasons to buy

- Understand how the prefilled syringe market has adapted to issues.
- Predict which innovations are likely to be most successful in the future.
- Gain an understanding of areas of unmet need in the market

  
Source:
Document ID
GBIHC258MR
Industry
Format:
PDF Adobe Acrobat
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Sections

TitleStarting PageNumber of Pages
Table of Contents42
  List of Figures51
Innovation in Prefilled Syringes - Overview61
  Overview61
Innovation in Prefilled Syringes - Introduction72
  What are Prefilled Syringes?71
  The Current Position of Prefilled Syringes in the Pharmaceutical Market71
  Factors Fueling Growth of Prefilled Syringes71
  Issues around the Use of Prefilled Syringes81
  Where Does Innovation Lie?81
Innovation in Prefilled Syringes - Current Device Technologies and Associated Drivers and Barriers94
  Glass Syringes versus Plastic Syringes91
    Fragility91
    Dimensional Variability91
    Siliconization91
    Delamination101
    Tungsten Contamination101
  Autoinjection Devices111
  Safety Devices on Prefilled Syringes111
  Prefilled Diluent Syringes121
  Biologics Driving Innovation in Prefilled Syringes121
Innovation in Prefilled Syringes - Formulation Considerations and Challenges for Pharmaceutical Companies132
  Drug Viscosity131
  Extractables and Leachables131
  Lyophilized Drugs versus Liquid-stable Formulations141
Innovations in Prefilled Syringes - Overcoming Current Barriers and Trends in Development1510
  Innovative Ways of Gaining Life Cycle Extensions for Existing Products151
  Plastic Syringes Offer Some Improvements over Traditional Glass Syringes161
    Polypropylene161
      Aguettant s Prefilled Syringe161
    Cyclo-olefin Polymers and Co-polymers161
      West Pharmaceuticals Daikyo Crystal Zenith Prefilled Syringe171
  Extractables and Leachables181
    Glass Coatings - Reducing Silicone and Silicone Baking181
    Coated Stoppers181
  Safety Innovations191
  Integrated Needles - Advancements on the Luer Lock System201
  Filling Technologies and Removing the Air Bubble201
  Needle Length - Reducing Length can Increase Accuracy of Subcutaneous Injections201
  Manufacturing Advances - Sterilizing Syringes211
    Restricted Access Barrier Systems211
    Electron Beam Sterilization Tunnels211
  Automating and Streamlining the Manufacture of Prefilled Syringes221
  Manufacturing Flexibility and Integrated Systems221
  Testing of Prefilled Syringes231
  Customization of Prefilled Syringes231
  Self-injection Improvements241
  Patient-centric Focus for CMOs241
Appendix254
  Market Definitions251
  Abbreviations251
  Bibliography251
  Research Methodology262
    Coverage261
    Secondary Research271
    Primary Research271
    Expert Panel Validation271
  Contact Us281
  Disclaimer281

Table Of Contents

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Cite this Report

  
MLA:
GBI Research Reports. "Innovation in the Prefilled Syringe Market - Biologics and Autoinjection Devices Shaping Future R&D Trends" Dec 14, 2012. Alacra Store. May 04, 2025. <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Innovation-in-the-Prefilled-Syringe-Market-Biologics-and-Autoinjection-Devices-Shaping-Future-R-D-Trends-2115-543>
  
APA:
GBI Research Reports. (2012). Innovation in the Prefilled Syringe Market - Biologics and Autoinjection Devices Shaping Future R&D Trends Dec 14, 2012. New York, NY: Alacra Store. Retrieved May 04, 2025 from <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Innovation-in-the-Prefilled-Syringe-Market-Biologics-and-Autoinjection-Devices-Shaping-Future-R-D-Trends-2115-543>
  
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