Sections
Title | Starting Page | Number of Pages |
---|
Table of Contents | 5 | 7 |
List of Tables | 8 | 2 |
List of Figures | 10 | 2 |
Generics in Cardiovascular Diseases Market to 2018 Introduction | 12 | 1 |
Generics in Cardiovascular Diseases Market to 2018 - Global Market Overview | 13 | 8 |
Introduction | 13 | 1 |
Antidyslipidemics | 13 | 2 |
Anti-Hypertensives | 15 | 1 |
Generics in Various Classes | 15 | 1 |
Rise in Generics in CVD Market | 15 | 1 |
Factors Responsible for Increasing Costs Associated with Generics and Soon-to-be Generics | 15 | 1 |
Revenue | 16 | 2 |
Annual Cost of Therapy | 18 | 1 |
Treatment Usage Patterns | 19 | 1 |
Disease population | 20 | 1 |
Treatment Seeking Population | 20 | 1 |
Diagnosed Population | 20 | 1 |
Prescription Population | 20 | 1 |
Generics in Cardiovascular Disease Market to 2018 - Geographical Landscape | 21 | 13 |
The US | 21 | 1 |
Revenue | 21 | 1 |
Annual Cost of Therapy | 22 | 2 |
Treatment Usage Patterns | 24 | 1 |
Disease population | 25 | 1 |
Treatment Seeking Population | 25 | 1 |
Diagnosed Population | 25 | 1 |
Prescription Population | 25 | 1 |
Top Five Countries of Europe | 26 | 1 |
Revenue | 26 | 1 |
Annual Cost of Therapy | 27 | 1 |
Treatment Usage Patterns | 28 | 1 |
Disease population | 29 | 1 |
Treatment Seeking Population | 29 | 1 |
Diagnosed Population | 29 | 1 |
Prescription Population | 29 | 1 |
Japan | 30 | 1 |
Revenue | 30 | 1 |
Annual Cost of Therapy | 31 | 1 |
Treatment Usage Patterns | 32 | 1 |
Disease population | 33 | 1 |
Treatment Seeking Population | 33 | 1 |
Diagnosed Population | 33 | 1 |
Prescription Population | 33 | 1 |
Generics in Cardiovascular Diseases Market to 2018- Therapeutic Landscape | 34 | 43 |
Thrombosis | 34 | 1 |
Introduction | 34 | 1 |
Revenue | 35 | 1 |
Annual Cost of Therapy | 36 | 1 |
Treatment Flow Algorithm | 37 | 1 |
Treatment Usage Pattern | 38 | 1 |
Disease population | 39 | 1 |
Treatment Seeking Population | 39 | 1 |
Diagnosed Population | 39 | 1 |
Prescription Population | 39 | 1 |
Drivers and Restraints | 40 | 1 |
Drivers | 40 | 1 |
Patent Expiries of Major Blockbuster Drugs | 40 | 1 |
Restraints | 40 | 1 |
Expected Launch of Promising Molecules | 40 | 1 |
Pulmonary Arterial Hypertension | 41 | 1 |
Introduction | 41 | 1 |
Pulmonary Arterial Hypertension | 41 | 1 |
Pulmonary Venous Hypertension | 41 | 1 |
Pulmonary Hypertension Associated With Hypoxemia | 42 | 1 |
Pulmonary Hypertension Due to Chronic Thrombotic and/or Embolic Disease | 42 | 1 |
Miscellaneous | 42 | 1 |
Diagnosis of PAH is Primarily Carried out in the Following Ways: | 42 | 1 |
Revenue | 43 | 1 |
Annual Cost of Therapy | 44 | 2 |
Treatment Usage Patterns | 46 | 1 |
Disease population | 47 | 1 |
Treatment-Seeking Population | 47 | 1 |
Diagnosed Population | 47 | 1 |
Prescription Population | 47 | 1 |
Treatment Flow Algorithm | 48 | 1 |
Drivers and Restraints | 48 | 1 |
Drivers | 49 | 1 |
Patent Expiry of Leading PAH Medication - Tracleer | 49 | 1 |
Continued Uptake of Epoprostenol | 49 | 1 |
Restraints | 49 | 1 |
Low Treatment Seeking Behavior and Diagnosis in Pulmonary Arterial Hypertension | 49 | 1 |
Expected To Launch of Novel Molecules Such As Macitentan and Riociguat | 49 | 1 |
Hypertension | 50 | 1 |
Introduction | 50 | 1 |
Revenue | 51 | 1 |
Annual Cost of Therapy | 52 | 1 |
Treatment Flow Algorithm for Hypertension | 53 | 1 |
Treatment Usage Patterns | 54 | 1 |
Disease population | 55 | 1 |
Treatment-Seeking Population | 55 | 1 |
Diagnosed Population | 55 | 1 |
Prescription Population | 55 | 1 |
Drivers and Restraints | 56 | 1 |
Drivers | 56 | 1 |
Patent Expiries of Major Blockbusters | 56 | 1 |
Rising Prevalence of Hypertension | 56 | 1 |
Restraints | 56 | 1 |
Increased Uptake of Combination Drugs | 56 | 1 |
Dyslipidemia Market | 57 | 1 |
Introduction | 57 | 1 |
Revenue | 57 | 2 |
Annual Cost of Therapy | 59 | 1 |
Treatment Flow Algorithm | 60 | 1 |
Treatment Usage Patterns | 61 | 1 |
Disease population | 62 | 1 |
Treatment Seeking Population | 62 | 1 |
Diagnosed Population | 62 | 1 |
Prescription Population | 62 | 1 |
Drivers and Restraints | 62 | 1 |
Drivers | 63 | 1 |
Patent Expiry of Lipitor | 63 | 1 |
Rising Prevalence of Dyslipidemia | 63 | 1 |
Restraints | 63 | 1 |
Expected Launch of Daralapib and Dalcetrapib | 63 | 1 |
Coronary Artery Disease | 64 | 1 |
Introduction | 64 | 1 |
Revenue | 64 | 2 |
Annual Cost of Therapy | 66 | 1 |
Treatment Usage Patterns | 67 | 1 |
Disease population | 68 | 1 |
Treatment Seeking Population | 68 | 1 |
Diagnosed Population | 68 | 1 |
Prescription Population | 68 | 1 |
Drivers and Restraints | 69 | 1 |
Drivers | 69 | 1 |
Rising Incidence of CAD | 69 | 1 |
Increasing Prescription Rates | 69 | 1 |
Drug Patent Expiries Leading to Increase in Generic Competition | 69 | 1 |
Restraints Market | 70 | 1 |
Promising Molecules in the Pipeline Dampen the Generics Market | 70 | 1 |
Angina Pectoris Market | 70 | 1 |
Introduction | 70 | 1 |
Revenue | 71 | 1 |
Cost of Therapy | 72 | 1 |
Treatment Flow Algorithm | 73 | 1 |
Treatment Usage Patterns | 74 | 1 |
Disease population | 75 | 1 |
Treatment Seeking Population | 75 | 1 |
Diagnosed Population | 75 | 1 |
Prescription Population | 75 | 1 |
Drivers and Restraints | 75 | 1 |
Drivers for the Angina Pectoris Market | 76 | 1 |
Rise of Geriatric Population | 76 | 1 |
Lifestyle Changes Increases Incidence of Angina | 76 | 1 |
Patent Expiry of Major Blockbuster Drug Lipitor | 76 | 1 |
Restraints for the Angina Pectoris Market | 76 | 1 |
Adverse Effects Associated with Current Drugs Reduces Prescription | 76 | 1 |
Generics in Cardiovascular Diseases Market to 2018 - Product Pipeline Analysis | 77 | 22 |
Introduction | 77 | 1 |
Research and Development Pipeline Pulmonary Arterial Hypertension | 78 | 3 |
Research and Development Pipeline Dyslipidemia | 81 | 6 |
Research and Development Pipeline Coronary Artery Disease | 87 | 2 |
Research and Development Pipeline Angina Pectoris | 89 | 1 |
Research and Development Pipeline Thrombosis | 89 | 3 |
Research and Development Pipeline Hypertension | 92 | 7 |
Generics in Cardiovascular Diseases Market to 2018 - Most Promising Pipeline Molecules | 99 | 3 |
Eliquis | 99 | 1 |
Introduction | 99 | 1 |
Mechanism of Action | 99 | 1 |
RG1658 (Dalcetrapib, JTT-705, RO4607381) | 99 | 1 |
Introduction | 99 | 1 |
Mechanism of Action | 99 | 1 |
Clinical Trial Management 1 | 99 | 1 |
MK-0524A (Cordaptive, niacin + laropiprant) | 100 | 1 |
Introduction | 100 | 1 |
Mechanism of Action | 100 | 1 |
Clinical Trial Management 2 | 100 | 1 |
AMR101 (LAX-101, Miraxion) | 101 | 1 |
Introduction | 101 | 1 |
Mechanism of Action | 101 | 1 |
Clinical Trial Management 3 | 101 | 1 |
Generics in Cardiovascular Diseases Market to 2018 Competitive Landscape | 102 | 2 |
Teva Pharma | 102 | 1 |
Sandoz | 102 | 1 |
Actavis | 102 | 1 |
Apotex | 102 | 1 |
Watson Pharmaceuticals | 103 | 1 |
Watson Launches First Generic Lipitor (atorvastatin) | 103 | 1 |
Mylan | 103 | 1 |
Generics in Cardiovascular Diseases Market to 2018 Strategic Consolidations | 104 | 18 |
Merger and Acquisition Deals (2004-2011) | 104 | 2 |
Deals by Year | 106 | 1 |
M&A Deals by Region | 107 | 1 |
M&A Deals by Value | 108 | 1 |
Deal Summary of Top 10 M&A Deals by Value | 109 | 1 |
Takeda Pharmaceutical Acquires Nycomed International for $13.7 Billion - 2011 | 109 | 1 |
Endo Pharmaceuticals Acquires Qualitest Pharmaceuticals - 2010 | 109 | 1 |
Celgene Acquires Abraxis BioScience -2010 | 109 | 1 |
Abbott Laboratories Acquires Solvay Pharmaceuticals for $7.6 Billion - 2009 | 109 | 1 |
Gilead Sciences Acquires CV Therapeutics - 2009 | 110 | 1 |
Daiichi Sankyo Acquires Majority Stake in Ranbaxy Laboratories - 2008 | 110 | 1 |
Eli Lilly Acquires ICOS - 2006 | 110 | 1 |
Sanofi-Synthelabo Merges with Aventis 2004 | 110 | 1 |
Licensing Deals | 111 | 2 |
Deals by Indication | 113 | 1 |
Deals by Geography | 114 | 1 |
Deals by Year | 115 | 1 |
Deal Summary of Top Five Licensing Deals by Value | 116 | 1 |
Amgen Enters Into a Licensing Agreement with Cytokinetics 2009 | 116 | 1 |
United Therapeutics Enters Into Licensing Agreement with Eli Lilly 2008 | 116 | 1 |
CV Therapeutics Enters Into Licensing Agreement with Menarini Group September 2008 | 116 | 1 |
GlaxoSmithKline Enters Into Licensing Agreement with Myogen 2006 | 116 | 1 |
Mylan Enters Into Licensing Agreement with Forest Laboratories 2006 | 116 | 1 |
Co-development Deals | 117 | 1 |
Deals by Indication | 117 | 1 |
Deals by Geography | 118 | 1 |
Deals by Year | 119 | 1 |
Deal Summary of Top Five Co-development Deals by Value | 120 | 1 |
Les Laboratoires Enters into Co-Development Agreement with miRagen Therapeutics | 120 | 1 |
Boehringer Ingelheim Enters Into Agreement with Vitae Pharmaceuticals | 120 | 1 |
Bristol-Myers Enters Into Co-Development Agreement with Pfizer | 120 | 1 |
Cytokinetics Signs Strategic Agreement with Amgen | 120 | 1 |
Metabolex Enters Into Co-Development Agreement with Ortho-Mcneil | 121 | 1 |
Generics in Cardiovascular Diseases Market to 2018 - Appendix | 122 | 8 |
Market Definitions | 122 | 1 |
Abbreviations | 122 | 1 |
Sources | 123 | 1 |
Research Methodology | 124 | 6 |
Coverage | 124 | 1 |
Secondary Research | 125 | 1 |
Primary Research | 125 | 1 |
The report consists of the following four major sections | 125 | 1 |
Therapeutic Landscape | 126 | 1 |
Epidemiology-based Forecasting | 126 | 1 |
Analogous Forecasting Methodology | 127 | 1 |
Disease population | 127 | 1 |
Treatment Seeking Population | 127 | 1 |
Diagnosis Population | 127 | 1 |
Prescription Population | 127 | 1 |
Forecasting Model for Therapeutic Areas | 128 | 1 |
Geographical Landscape | 129 | 1 |
Pipeline Analysis | 129 | 1 |
Competitive Landscape | 129 | 1 |
Expert Panel Validation | 129 | 1 |
Contact Us | 129 | 1 |
Disclaimer | 129 | 1 |