Sections
Title | Starting Page | Number of Pages |
---|
Table of Contents | 3 | 5 |
List of Tables | 5 | 1 |
List of Figures | 6 | 2 |
Introduction | 8 | 1 |
GBI Research Report Guidance | 8 | 1 |
Endpoints - Clinical Trials in Dermatology - Overview | 9 | 1 |
Endpoints Used for Regular Approval | 9 | 1 |
Safety and Efficacy | 9 | 1 |
Change in Inflammatory Lesion Counts | 9 | 1 |
Varicella Zoster Virus (VZV) Antibody Response | 9 | 1 |
Pain | 9 | 1 |
Endpoints - Clinical Trials in Dermatology - Marketed and Pipeline Products Assessment | 10 | 80 |
Alopecia | 10 | 1 |
Primary Endpoints in Alopecia | 10 | 1 |
Secondary Endpoints in Alopecia | 10 | 1 |
Major Marketed Drugs - Safety and Efficacy Analysis | 11 | 1 |
Propecia (finasteride) | 11 | 1 |
Rogaine (minoxidil) | 12 | 1 |
Kenalog-10 (triamcinolone acetonide) | 13 | 1 |
Phase III Molecules Analysis | 14 | 1 |
Phase III Primary Endpoint Analysis | 14 | 1 |
Phase III Secondary Endpoint Analysis | 15 | 2 |
Phase II Molecules Analysis | 17 | 1 |
Phase II Primary Endpoint Analysis | 17 | 1 |
Phase II Secondary Endpoint Analysis | 18 | 1 |
Terminated Trials | 19 | 1 |
Candidiasis | 19 | 1 |
Primary Endpoints in Candidiasis | 19 | 1 |
Secondary Endpoints in Candidiasis | 20 | 1 |
Major Marketed Drugs (Azole Group) - Safety and Efficacy Analysis | 21 | 1 |
Fluconazole | 21 | 1 |
Itraconazole | 22 | 1 |
Miconazole | 23 | 1 |
Clotrimazole | 24 | 1 |
Ketoconazole | 24 | 1 |
Major Marketed Drugs (Echinocandins Class) - Safety and Efficacy Analysis | 25 | 1 |
Anidulafungin | 25 | 1 |
Micafungin | 26 | 1 |
Major Marketed Drugs (Polyene class) - Safety and Efficacy Analysis | 27 | 1 |
Nystatin | 27 | 1 |
Phase III Molecules Analysis | 28 | 1 |
Phase III Primary Endpoint Analysis | 28 | 1 |
Phase III Secondary Endpoint Analysis | 29 | 3 |
Most Promising Drugs Profiles | 32 | 1 |
Voriconazole | 32 | 1 |
Posaconazole | 33 | 1 |
Phase II Molecules Analysis | 34 | 1 |
Phase II Primary Endpoint Analysis | 34 | 1 |
Phase II Secondary Endpoint Analysis | 34 | 2 |
Terminated Trials | 36 | 1 |
Atopic Dermatitis | 37 | 1 |
Primary Endpoints in Atopic Dermatitis | 37 | 1 |
Secondary Endpoints in Atopic Dermatitis | 37 | 1 |
Major Marketed Drugs - Safety and Efficacy Analysis | 38 | 1 |
Protopic | 38 | 1 |
Elidel | 39 | 1 |
MimyX | 40 | 1 |
Atopiclair | 41 | 1 |
Topical Corticosteroids | 41 | 1 |
Phase III Molecules Analysis | 42 | 1 |
Phase III Primary Endpoint Analysis | 42 | 1 |
Phase III Secondary Endpoint Analysis | 43 | 4 |
Most Promising Drugs Profiles | 47 | 1 |
PH-10 | 47 | 1 |
Phase II Molecules Analysis | 48 | 1 |
Phase II Primary Endpoint Analysis | 48 | 2 |
Phase II Secondary Endpoint Analysis | 50 | 4 |
Terminated Trials | 54 | 1 |
Herpes Zoster | 54 | 1 |
Primary Endpoints in Herpes Zoster | 54 | 1 |
Secondary Endpoints in Herpes Zoster | 55 | 1 |
Major Marketed Drugs - Safety and Efficacy Analysis | 55 | 1 |
Acyclovir (Zovirax) | 55 | 1 |
Valacyclovir (Valtrex) | 56 | 1 |
Famciclovir (Famvir) | 56 | 1 |
Zostavax (Zoster Vaccine Live) | 57 | 1 |
Phase III Molecules Analysis | 58 | 1 |
Phase III Primary Endpoint Analysis | 58 | 2 |
Phase III Secondary Endpoint Analysis | 60 | 2 |
Most Promising Drugs Profiles | 62 | 1 |
GSK1437173A | 62 | 1 |
ASP2151 | 62 | 1 |
FV-100 | 63 | 1 |
Phase II Molecules Analysis | 64 | 1 |
Phase II Primary Endpoint Analysis | 64 | 2 |
Phase II Secondary Endpoint Analysis | 66 | 2 |
Terminated Trials | 68 | 1 |
Acne Vulgaris | 69 | 1 |
Primary Endpoints in Acne Vulgaris | 69 | 1 |
Secondary Endpoints in Acne Vulgaris | 70 | 1 |
Major Marketed Drugs - Safety and Efficacy Analysis | 70 | 1 |
Solodyn | 70 | 1 |
Doryx | 71 | 1 |
Epiduo | 72 | 1 |
Duac | 73 | 1 |
Tazorac | 73 | 1 |
Ziana | 74 | 1 |
Differin | 75 | 1 |
Benzaclin | 76 | 1 |
Phase III Molecules Analysis | 77 | 1 |
Phase III Primary Endpoint Analysis | 77 | 2 |
Phase III Secondary Endpoint Analysis | 79 | 4 |
Most Promising Drugs Profiles | 83 | 1 |
Clindamycin + Tretinoin | 83 | 1 |
Phase II Molecules Analysis | 84 | 1 |
Phase II Primary Endpoint Analysis | 84 | 2 |
Phase II Secondary Endpoint Analysis | 86 | 3 |
Terminated Trials | 89 | 1 |
Endpoints - Clinical Trials in Dermatology - Company Profiles | 90 | 5 |
Merck | 90 | 1 |
Business Description | 90 | 1 |
Product Portfolio | 90 | 1 |
Propecia | 90 | 1 |
Zostavax | 90 | 1 |
Novartis | 91 | 1 |
Business Description | 91 | 1 |
Product Portfolio | 91 | 1 |
Elidel | 91 | 1 |
Famvir | 91 | 1 |
GlaxoSmithKline | 92 | 1 |
Business Description | 92 | 1 |
Product Portfolio | 92 | 1 |
Zovirax | 92 | 1 |
Valtrex | 92 | 1 |
Pfizer | 93 | 1 |
Business Description | 93 | 1 |
Product Portfolio | 93 | 1 |
Diflucan | 93 | 1 |
Eraxis | 93 | 1 |
Astellas Pharma | 93 | 1 |
Business Description | 93 | 1 |
Product Portfolio | 94 | 1 |
Mycamine | 94 | 1 |
Protopic | 94 | 1 |
Galderma | 94 | 1 |
Business Description | 94 | 1 |
Product Portfolio | 94 | 1 |
Epiduo | 94 | 1 |
Differin | 94 | 1 |
Endpoints - Clinical Trials in Dermatology - Appendix | 95 | 5 |
Market Definitions | 95 | 1 |
Abbreviations | 95 | 2 |
Research Methodology | 97 | 2 |
Major Dermatological Disorders and their Product Profiling | 97 | 1 |
Marketed and Pipeline Products Assessment | 98 | 1 |
Company Profiles | 98 | 1 |
Contact Us | 98 | 1 |
Disclaimer | 99 | 1 |
Sources | 99 | 1 |