Endpoints - Clinical Trials in Dermatology - Inflammatory Lesions Count is the Key Determinant of Success in Acne Vulgaris Clinical Trials - GBI Research Reports

Endpoints - Clinical Trials in Dermatology - Inflammatory Lesions Count is the Key Determinant of Success in Acne Vulgaris Clinical Trials

Endpoints - Clinical Trials in Dermatology - Inflammatory Lesions Count is the Key Determinant of Success in Acne Vulgaris Clinical Trials - GBI Research Reports
Endpoints - Clinical Trials in Dermatology - Inflammatory Lesions Count is the Key Determinant of Success in Acne Vulgaris Clinical Trials
Published Jan 01, 2012
99 pages — Published Jan 01, 2012
Price US$ 3,500.00  |  Buy this Report Now

About This Report

  
Abstract:

Summary

GBI Research, the leading business intelligence provider, has released its latest research Endpoints - Clinical Trials in Dermatology - Inflammatory Lesions Count is the Key Determinant of Success in Acne Vulgaris Clinical Trials which provides an insight into different endpoints that are used in dermatological clinical trials. The report examines different aspects under clinical trial endpoints in dermatology such as analysis on major marketed drugs with an emphasis on safety and efficacy details, Phase II and Phase III clinical trial analysis for both completed and ongoing clinical trials, most promising drugs with more emphasis on safety, efficacy and clinical trial details, and terminated trial analysis. The company profiling highlights the marketed drugs in dermatology of different companies.

Dermatological disorders are diverse in clinical presentation, severity and epidemiology; and it affects all age groups of both sexes, however; children are more vulnerable and have been studied worldwide. This report details Endpoints- Clinical Trials in Dermatology, highlighting the five major dermatological disorders which are Alopecia, Acne Vulgaris, Herpes Zoster, Candidiasis and Atopic Dermatitis. The classification of the five major dermatological disorders is based upon the number of pipeline molecules present in Phase III stage of development. GBI Research analyses that safety and efficacy is the most widely used endpoint in majority of the clinical trials in dermatology. The primary and secondary endpoint that is mainly used to assess the majority of trial outcomes is safety.

Scope

- Data and analysis on the marketed products and analysis of their efficacy and safety details.
- Analysis of the five major dermatological disorders which include Alopecia, Acne Vulgaris, Herpes Zoster, Candidiasis and Atopic Dermatitis.
- Analysis of the Phase III and Phase II clinical trials in terms of percentage cases. Also analysis of terminated trials is included in this chapter. Only industry sponsored studies are included in the report.
- Analysis on most promising molecules of five major dermatological disorders with emphasis on their efficacy and safety details.
- Company profiling talks in detail about the companies, which are strong in the market.

Reasons to buy

- Build effective strategies to launch their pipeline products by identifying potential geographies.
- Exploit in-licensing and out-licensing opportunities by identifying products that might probably fill their portfolio gaps.
- Align your product portfolio to the markets with high growth potential.
- Develop market-entry and market expansion strategies by identifying the leading therapeutic segments and geographic markets poised for strong growth.
- Reinforce R&D pipelines by identifying new target mechanisms which can produce first-in-class molecules with increased efficiency and better safety profiles.
- Develop key strategic initiatives by understanding the key focus areas of leading companies.

  
Source:
Document ID
GBIHC154MR
Industry
Format:
PDF Adobe Acrobat
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Sections

TitleStarting PageNumber of Pages
Table of Contents35
  List of Tables51
  List of Figures62
Introduction81
  GBI Research Report Guidance81
Endpoints - Clinical Trials in Dermatology - Overview91
  Endpoints Used for Regular Approval91
    Safety and Efficacy91
    Change in Inflammatory Lesion Counts91
    Varicella Zoster Virus (VZV) Antibody Response91
    Pain91
Endpoints - Clinical Trials in Dermatology - Marketed and Pipeline Products Assessment1080
  Alopecia101
    Primary Endpoints in Alopecia101
    Secondary Endpoints in Alopecia101
    Major Marketed Drugs - Safety and Efficacy Analysis111
      Propecia (finasteride)111
      Rogaine (minoxidil)121
      Kenalog-10 (triamcinolone acetonide)131
    Phase III Molecules Analysis141
      Phase III Primary Endpoint Analysis141
      Phase III Secondary Endpoint Analysis152
    Phase II Molecules Analysis171
      Phase II Primary Endpoint Analysis171
      Phase II Secondary Endpoint Analysis181
    Terminated Trials191
  Candidiasis191
    Primary Endpoints in Candidiasis191
    Secondary Endpoints in Candidiasis201
    Major Marketed Drugs (Azole Group) - Safety and Efficacy Analysis211
      Fluconazole211
      Itraconazole221
      Miconazole231
      Clotrimazole241
      Ketoconazole241
    Major Marketed Drugs (Echinocandins Class) - Safety and Efficacy Analysis251
      Anidulafungin251
      Micafungin261
    Major Marketed Drugs (Polyene class) - Safety and Efficacy Analysis271
      Nystatin271
    Phase III Molecules Analysis281
      Phase III Primary Endpoint Analysis281
      Phase III Secondary Endpoint Analysis293
    Most Promising Drugs Profiles321
      Voriconazole321
      Posaconazole331
    Phase II Molecules Analysis341
      Phase II Primary Endpoint Analysis341
      Phase II Secondary Endpoint Analysis342
    Terminated Trials361
  Atopic Dermatitis371
    Primary Endpoints in Atopic Dermatitis371
    Secondary Endpoints in Atopic Dermatitis371
    Major Marketed Drugs - Safety and Efficacy Analysis381
      Protopic381
      Elidel391
      MimyX401
      Atopiclair411
      Topical Corticosteroids411
    Phase III Molecules Analysis421
      Phase III Primary Endpoint Analysis421
      Phase III Secondary Endpoint Analysis434
    Most Promising Drugs Profiles471
      PH-10471
    Phase II Molecules Analysis481
      Phase II Primary Endpoint Analysis482
      Phase II Secondary Endpoint Analysis504
    Terminated Trials541
  Herpes Zoster541
    Primary Endpoints in Herpes Zoster541
    Secondary Endpoints in Herpes Zoster551
    Major Marketed Drugs - Safety and Efficacy Analysis551
      Acyclovir (Zovirax)551
      Valacyclovir (Valtrex)561
      Famciclovir (Famvir)561
      Zostavax (Zoster Vaccine Live)571
    Phase III Molecules Analysis581
      Phase III Primary Endpoint Analysis582
      Phase III Secondary Endpoint Analysis602
    Most Promising Drugs Profiles621
      GSK1437173A621
      ASP2151621
      FV-100631
    Phase II Molecules Analysis641
      Phase II Primary Endpoint Analysis642
      Phase II Secondary Endpoint Analysis662
    Terminated Trials681
  Acne Vulgaris691
    Primary Endpoints in Acne Vulgaris691
    Secondary Endpoints in Acne Vulgaris701
    Major Marketed Drugs - Safety and Efficacy Analysis701
      Solodyn701
      Doryx711
      Epiduo721
      Duac731
      Tazorac731
      Ziana741
      Differin751
      Benzaclin761
    Phase III Molecules Analysis771
      Phase III Primary Endpoint Analysis772
      Phase III Secondary Endpoint Analysis794
    Most Promising Drugs Profiles831
      Clindamycin + Tretinoin831
    Phase II Molecules Analysis841
      Phase II Primary Endpoint Analysis842
      Phase II Secondary Endpoint Analysis863
    Terminated Trials891
Endpoints - Clinical Trials in Dermatology - Company Profiles905
  Merck901
    Business Description901
    Product Portfolio901
      Propecia901
      Zostavax901
  Novartis911
    Business Description911
    Product Portfolio911
      Elidel911
      Famvir911
  GlaxoSmithKline921
    Business Description921
    Product Portfolio921
      Zovirax921
      Valtrex921
  Pfizer931
    Business Description931
    Product Portfolio931
      Diflucan931
      Eraxis931
  Astellas Pharma931
    Business Description931
    Product Portfolio941
      Mycamine941
      Protopic941
  Galderma941
    Business Description941
    Product Portfolio941
      Epiduo941
      Differin941
Endpoints - Clinical Trials in Dermatology - Appendix955
  Market Definitions951
  Abbreviations952
  Research Methodology972
    Major Dermatological Disorders and their Product Profiling971
    Marketed and Pipeline Products Assessment981
    Company Profiles981
  Contact Us981
  Disclaimer991
  Sources991

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Cite this Report

  
MLA:
GBI Research Reports. "Endpoints - Clinical Trials in Dermatology - Inflammatory Lesions Count is the Key Determinant of Success in Acne Vulgaris Clinical Trials" Jan 01, 2012. Alacra Store. May 14, 2025. <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Endpoints-Clinical-Trials-in-Dermatology-Inflammatory-Lesions-Count-is-the-Key-Determinant-of-Success-in-Acne-Vulgaris-Clinical-Trials-2115-319>
  
APA:
GBI Research Reports. (2012). Endpoints - Clinical Trials in Dermatology - Inflammatory Lesions Count is the Key Determinant of Success in Acne Vulgaris Clinical Trials Jan 01, 2012. New York, NY: Alacra Store. Retrieved May 14, 2025 from <http://www.alacrastore.com/storecontent/GBI-Research-Reports/Endpoints-Clinical-Trials-in-Dermatology-Inflammatory-Lesions-Count-is-the-Key-Determinant-of-Success-in-Acne-Vulgaris-Clinical-Trials-2115-319>
  
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