Sections
Title | Starting Page | Number of Pages |
---|
Table of Contents | 6 | 5 |
List of Tables | 10 | 1 |
List of Figures | 10 | 1 |
Diabetes Therapeutics Market in India to 2018 - Overview | 11 | 1 |
Diabetes Mellitus - A Global Overview | 11 | 1 |
Diabetes Therapeutics Market in India - Introduction | 12 | 5 |
Type 1 Diabetes Mellitus | 12 | 1 |
People at Risk | 12 | 1 |
Risk Factors for Type 1 Diabetes | 12 | 1 |
Symptoms | 12 | 1 |
Type 2 Diabetes Mellitus | 13 | 1 |
People at Risk | 13 | 1 |
Risk Factors for Type 2 Diabetes | 13 | 1 |
Symptoms | 13 | 1 |
Gestational Diabetes Mellitus | 13 | 1 |
Risk Factors for Gestational Diabetes Mellitus | 13 | 1 |
Diagnosis of Diabetes Mellitus | 14 | 1 |
Diabetes Treatment Guidelines - India | 15 | 1 |
Introduction | 15 | 1 |
Prevention of Diabetes | 15 | 1 |
Diabetes Treatment | 15 | 1 |
Non-Pharmacological Treatment | 16 | 1 |
Pharmacological Treatment | 16 | 1 |
Diabetes Mellitus Complications | 16 | 1 |
Diabetes Therapeutics Market in India to 2018 - Major Drug Classes | 17 | 8 |
Sulfonylureas | 17 | 1 |
Introduction | 17 | 1 |
Mechanism of Action | 17 | 1 |
Major Drugs | 18 | 1 |
Thiazolidinediones | 18 | 1 |
Introduction | 18 | 1 |
Mechanism of Action | 18 | 1 |
Example | 18 | 1 |
Biguanides | 19 | 1 |
Introduction | 19 | 1 |
Mechanism of Action | 19 | 1 |
Drug Products | 19 | 1 |
Meglitinides | 20 | 1 |
Introduction | 20 | 1 |
Mechanism of Action | 20 | 1 |
Major Drugs | 20 | 1 |
Alpha-Glucosidase Inhibitors | 21 | 1 |
Introduction | 21 | 1 |
Mechanism of Action | 21 | 1 |
Major Drugs | 21 | 1 |
Glucagon-Like Peptide Analogs and Agonists | 22 | 1 |
Description | 22 | 1 |
Mechanism of Action | 22 | 1 |
Major Drugs | 22 | 1 |
Dipeptidyl Peptidase-4 Inhibitors | 22 | 1 |
Description | 22 | 1 |
Mechanism of Action | 22 | 1 |
Major Drugs | 23 | 1 |
Glucagon-Like Peptide-1 Analogs vs. Dipeptidyl Peptidase-4 Inhibitors | 23 | 1 |
Insulin Preparations | 23 | 1 |
Introduction | 23 | 1 |
Types of Insulin | 23 | 1 |
Pre-mixed Insulin | 24 | 1 |
Long-acting Analogs | 24 | 1 |
Rapid-acting Analogs | 24 | 1 |
Others | 24 | 1 |
Diabetes Therapeutics Market in India to 2018 - Epidemiology | 25 | 5 |
Introduction | 25 | 2 |
Diabetes Population in India | 27 | 2 |
Diagnosed Population | 29 | 1 |
Treated Population | 29 | 1 |
Diabetes Therapeutics Market in India to 2018 - Revenue Forecasts | 30 | 3 |
Introduction | 30 | 1 |
Oral Anti-Diabetics Market | 31 | 1 |
Insulin Market | 31 | 1 |
Annual Cost of Therapy | 32 | 1 |
Diabetes Therapeutics Market in India to 2018 - Economic Burden of Diabetes in India | 33 | 2 |
Economic Burden of Diabetes in India | 33 | 1 |
Introduction | 33 | 1 |
Healthcare Expenditure on Diabetes in India | 33 | 1 |
Collaborative Efforts Necessary to Address the Rising Burden of Diabetes | 34 | 1 |
Diabetes Therapeutics Market in India to 2018 - Drivers and Barriers | 35 | 3 |
Market Drivers | 35 | 1 |
Aging Population, Sedentary Lifestyle and Unhealthy Diet is Driving the Diabetic Population in India | 35 | 1 |
Promising Molecules Offering Improved Clinical Outcomes Could Increase Patient Base on Therapy | 35 | 1 |
Untapped Areas Offer Promising Opportunities to Pharmaceutical Companies | 36 | 1 |
Market Barriers | 36 | 1 |
Low Diagnosis and Prescription Rate | 36 | 1 |
Highly Competitive Market Driven by Generics and Branded Generics Increases Pricing Pressure | 36 | 1 |
High Out-of-Pocket and Low Healthcare Expenditure on Diabetes | 37 | 1 |
Diabetes Therapeutics Market in India to 2018 - Unmet Needs | 38 | 1 |
Introduction | 38 | 1 |
High Cost of Therapy and Drug Safety Issues Affect Patient Compliance | 38 | 1 |
Unmet Need Creates Opportunities for Pharmaceutical Companies | 38 | 1 |
Diabetes Therapeutics Market in India to 2018 - Product Pipeline Analysis | 39 | 4 |
Profiles of Promising Molecules in R&D Development | 40 | 1 |
IN-105 (Oral Insulin) | 40 | 1 |
Product Description | 40 | 1 |
Mechanism of Action | 40 | 1 |
R&D Progress | 40 | 1 |
NN9068/IDegLira/degludec +/- liraglutide | 40 | 1 |
Product Description | 40 | 1 |
Mechanism of Action | 41 | 1 |
R&D Progress | 41 | 1 |
Dapagliflozin | 41 | 1 |
Product Description | 41 | 1 |
Mechanism of Action | 41 | 1 |
R&D Progress | 41 | 1 |
Canagliflozin/TA-7284 | 42 | 1 |
Product Description | 42 | 1 |
Mechanism of Action | 42 | 1 |
Lixisenatide | 42 | 1 |
Product Description | 42 | 1 |
Mechanism of Action | 42 | 1 |
Alogliptin | 42 | 1 |
Product Description | 42 | 1 |
Mechanism of Action | 42 | 1 |
Diabetes Therapeutics Market in India to 2018 - Case Studies | 43 | 3 |
Avandia Fallout Impact | 43 | 1 |
Introduction | 43 | 1 |
Cardiovascular Safety Issues | 43 | 1 |
Impact on GlaxoSmithKline | 43 | 1 |
Impact on Drug Approvals | 43 | 1 |
Januvia from Merck an Example that Patented Products can succeed in India | 44 | 1 |
Introduction | 44 | 1 |
Improved Pharmacological Effect of DPP-4 Inhibitors Helped Rapid Adoption | 44 | 1 |
Januvia and Janumet a New Growth Engine for Merck | 44 | 1 |
Robust Approach Needed to Market a New Drug Product in India | 44 | 1 |
Excellent Commercialization Strategy | 45 | 1 |
Conclusion | 45 | 1 |
Diabetes Therapeutics Market in India to 2018 - Major Trends and Issues | 46 | 9 |
Biguanides Class is dominated by Generics | 46 | 1 |
Evolving Oral Hypoglycemic Agents Resulting in Smaller Market Share Sulfonylureas | 46 | 1 |
Increasing Competition in Dipeptidyl Peptidase-4 Inhibitor Class | 46 | 1 |
DPP-4 Inhibitors Likely to Face Potential Competition from GLP-1 Agonists | 46 | 1 |
Thiazolidinedione Class to Face Impact of Avandia Fallout | 47 | 1 |
GLP-1 Agonists Must Demonstrate Better Safety and Efficacy Profiles to Compete with other Oral Hypoglycemic Class | 47 | 1 |
Fierce Competition in the Insulin Market is Likely to Increase | 48 | 1 |
Is Oral Insulin the Next Big Thing in the Insulin Market? | 48 | 1 |
Introduction | 48 | 1 |
Oral Insulin Not for All | 48 | 1 |
Challenges to Overcome | 48 | 1 |
Beating the Body s Defense Mechanism | 48 | 1 |
Dosing a Problems | 48 | 1 |
Would it lead to Market Cannibalization? | 49 | 1 |
India Diabetes Market: Setting up for the Biosimilars? | 49 | 1 |
Introduction | 49 | 1 |
Insulin Biosimilar Market | 49 | 1 |
Sanofi s Lantus a Lucrative Target | 49 | 1 |
Need for Dose Adjustments would Discourage Uptake of Biosimilars | 50 | 1 |
Price Discounts Alone would be Insufficient | 50 | 1 |
Strong Brand Promotion would be Necessary for Insulin Biosimilars | 50 | 1 |
Collaborations and Licensing Agreements are Key | 50 | 1 |
Conclusion | 51 | 1 |
Sodium Glucose Co-Transporter2 Inhibitors: A New Class to Hit the Market? | 51 | 1 |
Glucokinase Activators | 51 | 1 |
Stem Cell Therapies: The Next Prospective Therapy for Diabetes? | 52 | 1 |
Introduction | 52 | 1 |
What are Stem Cells? | 52 | 1 |
Stem Cell Therapies and Diabetes | 52 | 1 |
Conclusion | 52 | 1 |
Price Discounts a Decisive Factor in the Increasingly Competitive Anti-Diabetes Market | 53 | 1 |
Favorable Government Polices to Promote Generics | 53 | 1 |
Strategic Consolidation to Increase Growth Prospects | 54 | 1 |
Introduction | 54 | 1 |
Shift of Focus towards Rural and Class II-IV Towns | 54 | 1 |
Diabetes Therapeutics Market in India to 2018 - Competitive Landscape | 55 | 9 |
Novartis India Limited (Novartis India) | 55 | 1 |
Novo Nordisk India Private Limited (Novo) | 56 | 1 |
Eli Lilly and Company (India) Pvt. Ltd. (Eli Lilly) | 57 | 1 |
Merck Sharp Dohme India | 57 | 1 |
Abbott India Limited (Abbott India) | 58 | 1 |
Sun Pharmaceutical Industries Limited (Sun Pharma) | 59 | 1 |
USV Limited | 60 | 1 |
Wockhardt Limited (Wockhardt) | 61 | 1 |
Sanofi India Limited | 62 | 1 |
Biocon Limited (Biocon) | 63 | 1 |
Diabetes Therapeutics Market in India to 2018 - Strategic Consolidations | 64 | 3 |
Introduction | 64 | 1 |
Diabetology Entered into Licensing Agreement with USV for Capsulin on July 31, 2012 | 64 | 1 |
Merck Sharp &Dohme Entered into Co-Marketing Agreement with Sun Pharma on April 25, 2011 | 64 | 1 |
Eli Lilly and Company (India) Entered into Co-Promotion Agreement with Lupin on July 29, 2011 | 65 | 1 |
Sheffield Bio-Science Entered into Collaboration with Wockhardt on February 21, 2011 | 65 | 1 |
Eli Lilly Entered into Co-Promotion Agreement with Boehringer Ingelheim for Humalog and Linagliptin on October 3, 2011 | 65 | 1 |
Novartis India Entered into Co-Marketing Agreement with USV on December 31, 2008 | 65 | 1 |
Pfizer-Biocon Deal Called Off in March 2012 | 66 | 1 |
Impact Analysis | 66 | 1 |
Diabetes Therapeutics Market in India to 2018 - Appendix | 67 | 8 |
Market Definitions | 67 | 1 |
Abbreviations | 67 | 1 |
Bibliography | 68 | 1 |
Research Methodology | 69 | 2 |
Coverage | 69 | 1 |
Secondary Research | 70 | 1 |
Primary Research | 70 | 1 |
Therapeutic Landscape | 71 | 3 |
Market | 73 | 1 |
Geographical Landscape | 74 | 1 |
Pipeline Analysis | 74 | 1 |
Competitive Landscape | 74 | 1 |
Expert Panel Validation | 74 | 1 |
Contact Us | 74 | 1 |
Disclaimer | 74 | 1 |