Despite strong revenue growth, Huvepharma EOOD under-achieved our base-case scenario in 2019 because of slower-than-expected returns on investment and some profitability erosion, with S&P Global Ratings-adjusted debt to EBITDA increasing to 3.9x, from our initial estimate of 2.5x-3.0x. We believe the completion of strategic investment projects will gradually translate into profitable growth. However, we anticipate that S&P Global Ratings-adjusted debt to EBITDA will not improve to below 2.5x before 2022, owing to the high peak posted last year. We are therefore revising the outlook to stable from positive and affirming the 'BB' long-term issuer credit rating on Huvepharma. The stable outlook reflects our expectation of strong and profitable revenue growth in 2020 such that S&P Global Ratings-adjusted debt to EBITDA