We have updated our projections for Albany, N.Y.-based pharmaceutical contract development and manufacturing organization (CDMO) Curia Global Inc. (formerly Albany Molecular Research Inc.) and now expect cash flow generation in 2022-2023 to be negative due to higher expenses and growth spending. As a result, we lowered our issuer credit rating on Curia to 'B-' from 'B.' We also lowered our issue-level rating on the senior secured credit facility to 'B-' from 'B'. The recovery rating on this debt is unchanged at '3'. The outlook is stable and reflects our expectation for high-single-digit percent revenue growth and for profitability to begin to stabilize in 2023. We also expect that Curia will generate free cash flow deficits due to higher growth spending