U.S.-based global sampling provider Bioplan USA Inc. has underperformed our expectations since its merger in September 2014. We are lowering our corporate credit rating on Bioplan to 'B-' from 'B'. We are also lowering our issue-level ratings on the company's first-lien debt to 'B' from 'B+' and second-lien term loan to 'CCC+' from 'B-'. The recovery ratings remain unchanged. The negative rating outlook on Bioplan reflects the risk that the company may not be able to reverse its negative operating trends and its discretionary cash flow could remain negative in 2016. On Jan. 15, 2016, Standard&Poor's Ratings Services lowered its corporate credit rating on U.S.-based global sampling provider Bioplan USA Inc. to 'B-' from 'B'. The rating outlook