Overview Key strengths Key risks A market-leading position in the high-margin, patent-protected market for prescription drugs, which is relatively insensitive to the business cycle. Elevated risk of mergers and acquisitions (M&A) that could harm credit metrics given prospects for flat to declining revenue in 2025-2028, stemming from the Inflation Reduction Act (IRA) legislation and the loss of exclusivity (LOE) on key products. Nine blockbuster drugs in 2023 with franchises in oncology and hematology, immunology, cardiovascular disease, and neuroscience. Product concentration is higher than most peers, with the top three products accounting for about 61% of 2023 revenue (27%, 20%, and 14%, respectively). Long-standing commitment to a relatively conservative financial policy, with leverage expected to generally remain in the 2.0x-2.5x range,