Sections |
| Title | Starting Page | Number of Pages |
|---|
| Company Information | 1 | 1 |
| Shionogi & Co., Ltd. [NonUS -- Symbol : Stock Code Number : 4507 (The Tokyo Stock Exchange)] | 1 | 1 |
| Formation Date: 1878 | 1 | 1 |
| Business Summary | 1 | 1 |
| Upcoming Milestones for Shionogi & Co., Ltd. | 3 | 1 |
| Milestone | 3 | 1 |
| Date Category | 3 | 1 |
| Product Glance | 3 | 2 |
| Product Summary | 5 | 1 |
| Partner | 5 | 5 |
| Description | 9 | 2 |
| Therapeutic | 9 | 4 |
| Trial Details | 9 | 1 |
| Last Updated | 9 | 1 |
| 4. Vancomycin hydrochloride | 10 | 1 |
| Drug Class | 10 | 1 |
| Current Trial | 10 | 2 |
| Trial Details | 11 | 2 |
| 11. Humulin | 11 | 1 |
| Drug Class | 12 | 5 |
| Partnering Details | 12 | 1 |
| 12. Longes (lisinopril) | 12 | 1 |
| 13. Aqupla (nedaplatin) | 12 | 1 |
| Description | 13 | 3 |
| Current Trial | 13 | 3 |
| Last Updated | 13 | 1 |
| Trial Details | 14 | 3 |
| 18. Crestor (rosuvastatin calcium) | 14 | 1 |
| 20. Claritin (loratadine) | 15 | 1 |
| Therapeutic | 16 | 7 |
| 22. MH-200 (morphine hydrochloride) | 16 | 1 |
| 23. Popon-C white | 16 | 1 |
| Last Updated | 17 | 17 |
| Description | 17 | 6 |
| Current Trial | 17 | 5 |
| 27. Sedes Cure | 18 | 1 |
| 28. Finibax (doripenem) | 19 | 1 |
| Trial Details | 19 | 1 |
| 29. Cedax (ceftibuten) | 20 | 1 |
| Partnering Details | 20 | 1 |
| Drug Class | 21 | 1 |
| Trial Details | 21 | 1 |
| 31. Avelox (moxifloxacin hydrochloride) | 21 | 1 |
| 34. Tamiflu (oseltamivir phosphate) | 22 | 1 |
| Trial Details | 23 | 2 |
| Partnering Details | 23 | 5 |
| Therapeutic | 24 | 6 |
| Current Trial | 24 | 2 |
| Description | 24 | 8 |
| 37. Cetrotide (cetrorelix acetate) | 25 | 1 |
| 38. Zovirax (aciclovir) | 25 | 1 |
| Trial Details | 26 | 6 |
| 39. Zovirax (aciclovir) | 26 | 1 |
| 41. Sedes V | 27 | 1 |
| Drug Class | 28 | 1 |
| 45. Claritin Dry Syrup (loratadine) / SCH29851 | 29 | 1 |
| Current Trial | 29 | 2 |
| 48. LY 248686 (duloxetine AD) | 30 | 1 |
| Therapeutic | 31 | 1 |
| 49. Cetrorelix pamoate | 31 | 1 |
| Drug Class | 31 | 1 |
| Partnering Details | 32 | 5 |
| Current Trial | 33 | 13 |
| 51. LY 248686 (duloxetine hydrochloride) | 33 | 1 |
| Description | 33 | 1 |
| Therapeutic | 34 | 3 |
| Trial Details | 34 | 2 |
| 53. SB737004 | 34 | 1 |
| Last Updated | 35 | 2 |
| Description | 35 | 4 |
| Drug Class | 36 | 1 |
| Trial Details | 37 | 3 |
| Partnering Details | 38 | 1 |
| 63. RSC-1838 | 38 | 1 |
| Therapeutic | 39 | 2 |
| Last Updated | 39 | 1 |
| Drug Class | 39 | 2 |
| 67. Capravirine | 40 | 1 |
| Description | 40 | 2 |
| Trial Details | 41 | 3 |
| Partnering Details | 41 | 2 |
| Therapeutic | 42 | 1 |
| Description | 43 | 2 |
| Drug Class | 43 | 3 |
| 75. S-6820 (teceleukin) | 43 | 1 |
| Last Updated | 44 | 1 |
| Therapeutic | 45 | 1 |
| Trial Details | 45 | 2 |
| Corporate Partners | 47 | 1 |
| Deal Category: Miscellaneous | 47 | 1 |
| Partner | 47 | 1 |
| Deal Category: Product | 48 | 1 |
| Deal Value (in $ MM) | 48 | 4 |
| Kiyoshi Miyamoto -- Chairman and Representative Director | 52 | 1 |
| Motozo Shiono -- President | 52 | 1 |
| Masami Morita -- General Manager, Cancer Pain Management | 52 | 1 |
| Norio Yamada -- General Manager, Quality Assurance Unit | 52 | 1 |
| Isao Teshirogi -- Director | 52 | 1 |
| Yasuhiro Mino -- Director | 52 | 1 |
| Sachio Tokaji -- Director | 52 | 1 |
| Company Announcements | 53 | 1 |
| 5/15/2007 -- Shionogi Announces an Amendment to Its Articles of Incorporatiojn | 53 | 1 |
| 4/16/2007 -- Shionogi Announces the Opening of Drug Discovery Competition "FINDS" | 53 | 1 |
| 4/4/2007 -- Shionogi Announces Revisions to the Second Medium-Term Business Plan | 53 | 1 |
| 3/26/2007 -- Shionogi Announces Organizational and Personnel Changes | 53 | 1 |
| 4/25/2005 -- The Second Medium-Term Management Plan | 53 | 1 |
| 11/22/2004 -- Position Regarding Media Reports on November 18, 2004 | 53 | 1 |
| 4/19/2004 -- Introduction of New Retirement Benefit System | 54 | 1 |
| 7/24/2003 -- Announcement of Change of Launch Schedule for New Treatment for Hyperlipidemia Rosuvastatin Calcium | 54 | 1 |
| 5/19/2003 -- Notice of Outplacement Support Program and Other Matters | 54 | 1 |
| 5/20/2002 -- Acquisition of Treasury Stock | 54 | 1 |
| 4/1/2002 -- Shionogi & Co., Ltd. Announces Clinical Testing Service Joint Venture Commences Operations | 54 | 1 |
| 4/1/2002 -- Boehringer Ingelheim and Shionogi & Co. Ltd. Announces Boehringer Ingelheim Shionogi Vetmedica Commences Operatio | 54 | 1 |
| 3/25/2002 -- Shionogi & Co., Ltd. Announces 7 Branches and 3 Consolidated Subsidiaries Accredited to ISO14001 | 55 | 1 |
| 5/14/2001 -- Shionogi & Co., Ltd. Announces Establishment of Shionogi USA, Inc. | 55 | 1 |
| 3/28/2001 -- Shionogi & Co., Ltd. Announces Introduction of Invention Compensation System | 55 | 1 |
| 8/10/1998 -- Shionogi & Co., Ltd. Announces Establishment of the Manufacturing Subsidiary | 55 | 1 |
| 7/2/1997 -- Foundation of Shionogi BioResearch Corp.-US Subsidiary Aimed at the Discovery of New Drugs | 55 | 1 |
| Deals & Alliances | 55 | 1 |
| 3/5/2007 -- BioCryst and Shionogi Establish Collaboration in Japan | 56 | 1 |
| 2/2/2007 -- Eli Lilly Japan and Shionogi toCo-Develop and Co-Market Duloxetine in Japan | 56 | 1 |
| 10/5/2006 -- Shionogi & Co., Ltd.: Basic Agreement Reached on Construction of Joint Research Facility | 56 | 1 |
| 9/6/2006 -- Anthera Licenses Portfolio of Anti-Inflammatory from Eli Lilly and Company and Shionogi & Co., Ltd. | 56 | 1 |
| 3/8/2006 -- Shionogi, Galderma to Promote Acne Medicine Adapalene in Japan | 56 | 1 |
| 9/8/2005 -- MorphoSys Announces Agreement with Japanese Pharmaceutical Company Shionogi | 57 | 1 |
| 11/30/2004 -- Shionogi & Co., Ltd. Sale Marks Further Success For Inpharmatica's Biopendium In Japan | 57 | 1 |
| 10/19/2004 -- PDI, Inc. To Promote Shionogi & Co., Ltd.'s Cedax <br> | 57 | 1 |
| 8/30/2004 -- Distribution and Marketing of Cedax in the United States | 57 | 1 |
| 7/28/2004 -- License Agreement between Enanta and Shionogi | 57 | 1 |
| 12/8/2003 -- Basic Agreement on Transfer of Manufacturing Operations for Agrochemical and Animal Health | 58 | 1 |
| 10/22/2003 -- Shionogi begins a novel glycoprotein research effort with Hokkaido University | 58 | 1 |
| 10/17/2003 -- Bayer Yakuhin, Ltd. and Shionogi &Co., Ltd. Form Alliance to Distribute Moxifloxacin in Japan | 58 | 1 |
| 6/24/2003 -- Degussa and Shionogi establish Precipitated Silica/Silica Gel/Matting Agents Joint Venture in Japan | 58 | 1 |
| 5/26/2003 -- Licensing Agreement with Peninsula Pharmaceuticals, Inc.of the U.S. | 58 | 1 |
| 3/3/2003 -- Shionogi and GlaxoSmithKline to Co-promote the Anti-viral Agents | 58 | 1 |
| 10/30/2002 -- Pharmagene Laboratories Limited signs four access agreements with Shionogi & Co., Ltd. | 58 | 1 |
| 10/17/2002 -- Shionogi & Co., Ltd. and Kyowa Medex Co., Ltd. Announces Conclusion of the Agreement on the BNP Test Reagent | 59 | 1 |
| 8/6/2002 -- Shionogi & Co., Ltd. and Oncotherapy Science Inc. Announces of Business Collaboration on Human Genome-Based Drug | 59 | 1 |
| 5/16/2002 -- Shionogi and AstraZeneca Announces to Co-market Rosuvastatin Calcium, a New Treatment for Dyslipidaemia | 59 | 1 |
| 11/20/2001 -- Shionogi & Co., Ltd. and SRL Co., Ltd. Announces Basic Agreement Reached on Joint Venture for Clinical Testing | 59 | 1 |
| 10/23/2001 -- Shionogi & Co., Ltd. and GlaxoSmithKline plc Announces Final Agreement Reached on | 59 | 1 |
| GSK-Shionogi Joint Venture Project | 60 | 1 |
| 10/16/2001 -- Boehringer Ingelheim and Shionogi Announces to Form Joint Venture in the Animal Health Business | 60 | 1 |
| 9/25/2001 -- Shionogi & Co., Ltd. and Aventis CropScience S.A. Announces Establishment of Aventis CropScience Shionogi K.K. | 60 | 1 |
| 7/24/2001 -- GSK and Shionogi to Enter Global Multi-Product Development and Commercialization Alliance | 60 | 1 |
| 7/11/2001 -- Announcement of business partnership agreement signing by our subsidiary | 60 | 1 |
| 1/22/2001 -- Shionogi & Co., Ltd. Announces Co-promotion Deal on Anti-A and B Type Influenza Agent Developed by Nippon Roche | 61 | 1 |
| 1/19/2001 -- Shionogi & Co., Ltd. Announces Co-marketing of an Anti-Allergy Product | 61 | 1 |
| 6/29/1998 -- Shionogi & Co., Ltd. Announces Licensing Out of an Anti-HIV Compound to Agouron Pharmaceuticals, Inc. | 61 | 1 |
| Financials | 61 | 1 |
| 3/23/2005 -- Notice of Repurchase of Shares | 61 | 1 |
| 1/31/2005 -- Notice of Repurchase of Shares | 61 | 1 |
| 5/19/2003 -- Shionogi & Co., Ltd. Announces Acquistion of Treasury Stock | 62 | 1 |
| Mergers & Acquisitions | 62 | 1 |
| 1/27/2003 -- Shionogi to Merge Six Subsidiaries by Absorption | 62 | 1 |
| 5/7/1998 -- Shionogi & Co., Ltd. Announces Merger of 11 Subsidiary Wholesalers | 62 | 1 |
| Product Update | 62 | 1 |
| 9/18/2007 -- Roche Announces Tamiflu Will be in Ample Supply for 2007-2008 Flu Season | 62 | 1 |
| 4/19/2007 -- AEterna Zentaris Reports First Patients Treated with Cetrorelix for Phase III Program in BPH | 62 | 1 |
| 3/22/2007 -- AEterna Zentaris Reports Positive Results with Cetrorelix in BPH for Japanese Phase IIa Trial | 63 | 1 |
| 3/9/2007 -- Roche Files Supplemental New Drug Application with U.S. Food & Drug Administration for Tamiflu 30 mg and 45 mg Ca | 63 | 1 |
| 2/16/2007 -- Roche Files Application in Europe for Tamiflu 30 and 45 Mg Capsules | 63 | 1 |
| 2/5/2007 -- Shionogi Launches Cancer Pain Analgesic OxiNorm Powder 0.5% | 63 | 1 |
| 12/2/2006 -- Shionogi & Co., Ltd. Announces Results of Phase III Clinical Trials of the Idiopathic Pulmonary Fibrosis Tr 7701 | 64 | 1 |
| 11/29/2006 -- AEterna Zentaris to Initiate Phase III Program with Cetrorelix in BPH | 64 | 1 |
| 10/27/2006 -- Shionogi Discontinues Development of S-5751, a Prostaglandin D2 Receptor Antagonist | 64 | 1 |
| 9/21/2006 -- AEterna Zentaris Launches Cetrotide (cetrorelix) in Japan for In Vitro Fertilization | 64 | 1 |
| 8/15/2006 -- Glaxosmithkline And Shionogi Complete Initial Clinical Study For HIV Integrase Inhibitor | 64 | 1 |
| 7/7/2006 -- Shionogi to Launch Non-pyrazolone Antipyretic Analgesic "Sedes V" | 65 | 1 |
| 6/9/2006 -- Shionogi Launches Carbapenem Antibiotic Product "Finibax 0.25g IV Solution Kit" (Doripenem Hydrate) | 65 | 1 |
| 12/20/2005 -- Enanta Pharmaceuticals, Inc. Achieves Milestone in Alliance with Shionogi & Co., Ltd. | 65 | 1 |
| 12/9/2005 -- Shionogi Launches New Quinolone Antibacterial "Avelox Tablet 400mg" | 65 | 1 |
| 9/16/2005 -- Shionogi Launches Carbapenem Antibiotic "Finibax 0.25g IV Solution" (Doripenem Hydrate) | 65 | 1 |
| 9/15/2005 -- Shionogi Launches Carbapenem Antibiotic Finibax 0.25g IV Solution | 65 | 1 |
| 6/16/2005 -- Launch of Sedes cure | 65 | 1 |
| 4/27/2005 -- Hypercholesterolaemia treatment drug Crestor Launched | 66 | 1 |
| 3/16/2005 -- AEterna Zentaris Announces Decision to Continue Cetrorelix Development in Benign Prostate Hyperplasia in Japan | 66 | 1 |
| 3/2/2005 -- Labeling Revision For CRESTOR Approved By FDA | 66 | 1 |
| 1/19/2005 -- Hypercholesterolaemia Treatment Drug Crestor Approved | 66 | 1 |
| 12/27/2004 -- Regulatory Approval be Granted for Rosuvastatin Calcium | 66 | 1 |
| 11/30/2004 -- Launch Announcement of Popon-C white | 66 | 1 |
| 11/16/2004 -- Shionogi & Co., Ltd. Schering-Plough Corporation to Jointly Market Claritin RediTabs Tablet | 66 | 1 |
| 11/12/2004 -- Launch Announcement of Claritin RediTabs, 10mg Tablet | 67 | 1 |
| 11/5/2004 -- Eli Lilly Japan K.K. (LLY) Receives Additional Approval For Vancomycin Hydrochloride For Injection | 67 | 1 |
| 7/7/2003 -- Launch Announcement of Controlled-Released Oral Analgesic for Cancer Pain | 67 | 1 |
| 8/30/2002 -- Shionogi & Co., Ltd. Announces Launch of Anti-Allergic Product Claritin 10mg | 67 | 1 |
| 8/27/2002 -- Shionogi & Co., Ltd. Announces Notice of Additional Clinical Trials for Anti-Depressant Duloxetine | 67 | 1 |
| 7/10/2002 -- Shionogi & Co., Ltd. Announces Results of First Human Trial of A New Class of Anti-HIV Drugs Reported by Shionog | 67 | 1 |
| Regulatory | 68 | 1 |
| 7/23/2007 -- Smaller Size Capsules of Flu Drug Tamiflu Receive Positive Opinion in Europe | 68 | 1 |
| 10/20/2006 -- Shionogi Obtains Manufacturing, Marketing Approval for Oxinorm Powder 0.5% | 68 | 1 |
| 8/7/2006 -- The Analysis from the Interim Report of Post-marketing Surveillance Submitted to the Regulatory Authority | 68 | 1 |
| 4/21/2006 -- Shionogi, Nippon Kayaku Receive Approval for Cetrotide | 68 | 1 |
| 10/11/2005 -- Bayer Yakuhin Ltd. granted the importing rights for Avelox Tablet | 68 | 1 |
| 7/25/2005 -- Shionogi receives approval to Manufacture and Market Carbapenem Antibiotic Finibax; 0.25g IV Solution | 68 | 1 |
| 7/8/2002 -- Shionogi & Co., Ltd. and Schering-Plough K.K. Announces Approval of an Anti-Allergic Product | 69 | 1 |
Tables |
| Title | Starting Page | Number of Pages |
|---|
| of Contents | 2 | 1 |
