Sections |
| Title | Starting Page | Number of Pages |
|---|
| CHAPTER ONE Executive Summary | 13 | 1 |
| OVERVIEW | 13 | 3 |
| SCOPE AND METHODOLOGY | 15 | 2 |
| INTRODUCTION | 16 | 1 |
| THE DRUG DISCOVERY PROCESS AND OUTSOURCING | 18 | 2 |
| THE OUTSOURCING DECISION | 20 | 3 |
| OFFSHORING CONTRACT DRUG DISCOVERY | 22 | 4 |
| DRUG DISCOVERY OUTSOURCING MARKET | 26 | 2 |
| Op 200 | 28 | 1 |
| CHAPTER TWO Introduction | 29 | 1 |
| OVERVIEW | 29 | 3 |
| OUTSOURCING DRUG DISCOVERY | 31 | 3 |
| THE OUTSOURCING DECISION | 33 | 5 |
| SELECTING A CONTRACT RESEARCH ORGANIZATION | 37 | 2 |
| GLOBAL OUTSOURCING | 39 | 2 |
| CHAPTER THREE The Drug Discovery Process | 41 | 1 |
| INTRODUCTION -- DISCOVERY STAGES | 41 | 4 |
| ACCELERATING THE DRUG DISCOVERY PROCESS | 44 | 1 |
| TECHNOLOGIES USED IN DRUG DISCOVERY | 45 | 6 |
| ADDRESSING BOTTLENECKS IN THE DRUG DISCOVERY PROCESS | 50 | 1 |
| OUTSOURCING TO INCREASE EFFICIENCY | 50 | 4 |
| CHAPTER FOUR Outsourcing Drug Discovery | 55 | 1 |
| OVERVIEW | 55 | 2 |
| CONTRACT RESEARCH ORGANIZATIONS | 57 | 5 |
| OFFSHORING CONTRACT DRUG DISCOVERY | 61 | 4 |
| OUTSOURCING TO CHINA | 64 | 5 |
| OUTSOURCING TO INDIA | 68 | 5 |
| OUTSOURCING TO EASTERN EUROPE | 72 | 1 |
| CHAPTER FIVE Drug Discovery Outsourcing Market | 75 | 1 |
| OVERVIEW | 75 | 2 |
| CURRENT MARKET SIZE AND FORECAST | 76 | 2 |
| CONTRACT DRUG DISCOVERY COMPETITORS | 77 | 2 |
| MARKET ANALYSIS BY SEGMENT | 79 | 11 |
| MARKET GROWTH EXPANDING GLOBAL REACH OF DRUG DISCOVERY SERVICES | 91 | 1 |
| CHAPTER SIX Competitor Profiles | 93 | 1 |
| ALBANY MOLECULAR RESEARCH, INC. | 93 | 1 |
| Overview | 93 | 15 |
| ASINEX LTD. | 96 | 1 |
| BIODURO, INC. | 98 | 1 |
| BRIDGE LABORATORIES | 100 | 1 |
| CALIPER LIFE SCIENCES | 103 | 1 |
| CHARLES RIVER LABORATORIES, INC. | 105 | 1 |
| CHEMBIOTEK RESEARCH | 107 | 1 |
| CHEMBRIDGE RESEARCH LABORATORIES, INC. | 109 | 1 |
| Overview | 109 | 41 |
| CHEMICAL DIVERSITY INC. | 111 | 1 |
| DECODE CHEMISTRY AND BIOSTRUCTURES | 113 | 1 |
| ENAMINE LTD. | 116 | 1 |
| EVOTEC OAI | 118 | 1 |
| GVK BIOSCIENCES PRIVATE LIMITED | 121 | 1 |
| HUTCHISON MEDIPHARMA LTD. | 123 | 1 |
| J-STAR RESEARCH, INC. | 126 | 1 |
| JUBILANT BIOSYS LTD. | 127 | 1 |
| MDS PHARMA SERVICES | 131 | 1 |
| MEDICILON INC. | 133 | 1 |
| PHARMACOPEIA DRUG DISCOVERY, INC. | 135 | 1 |
| RICERCA BIOSCIENCES, LLC | 138 | 1 |
| SCYNEXIS, INC. | 140 | 1 |
| SHANGHAI CHEMPARTNER CO.,LTD. | 143 | 1 |
| WUXI PHARMATECH CO. LTD. | 147 | 1 |
| APPENDIX Company Directory | 151 | 13 |
| Disclosure | 163 | 1 |
Tables |
| Title | Starting Page | Number of Pages |
|---|
| Exhibit 2-2 Global R&D Spending 1996-2007 | 31 | 1 |
| Exhibit 3-3 Bioinformatics/Pharmacogenomics: The Role of the "-Omics" | 46 | 1 |
| Exhibit 4-1 Major Chinese Drug Discovery CROs (Company, Location, Services) | 66 | 1 |
| Exhibit 4-2 Major Indian Drug Discovery CROs (Company, Location, Services) | 70 | 1 |
| Exhibit 4-3 Major CROs Operating in Russia and the Ukraine | 73 | 1 |
| Exhibit 5-1 Global Drug Discovery Outsourcing Market 2005-2013 | 76 | 1 |
| Exhibit 5-2 Contract Drug Discovery Services by Market Segment (Chemistry, Biology, High-Throughput Sc 2005-2013 | 77 | 1 |
| Exhibit 5-3 Leading Contractors by Market Segment | 78 | 1 |
| Exhibit 5-4 Major Acquisitions in Drug Discovery Outsourcing | 78 | 1 |
| Exhibit 5-6 Chemistry Services Market: Revenues, Annual Growth, and Share of the Outsourced Drug Disco 2005-2013 | 82 | 1 |
| Exhibit 5-7 Chemistry Market Revenue by Service Type (Building Blocks, Compound Synthesis, Libraries, Proce 2007 | 82 | 1 |
| Exhibit 5-8 Biology Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discovery M 2005-2013 | 84 | 1 |
| Exhibit 5-9 Biology Market Revenue by Service Type (Protein Expression, Structural Analysis, Target Validat 2007 | 85 | 1 |
| Exhibit 5-10 Screening Services Market: Revenues, Annual Growth, and Share of Outsourced Drug Discover 2005-2013 | 87 | 1 |
| Exhibit 5-11 Screening Services Market Revenue by Service Type (Assay Development, Primary Screening, Secon 2007 | 88 | 1 |
| Exhibit 5-12 Lead Optimization Services Market: Revenues, Annual Growth, and Share of Outsourced Drug 2005-2013 | 90 | 1 |
| Exhibit 5-13 Lead Optimization Services Market by Service Type (Early ADME/Tox, Create Analogues,Computatio 2007 | 90 | 1 |
| Exhibit 5-14 Global Expansion of Drug Discovery Services: A Selection of Companies Expanding East and West | 92 | 1 |
Graphs |
| Title | Starting Page | Number of Pages |
|---|
| Exhibit 1-1 Drug Discovery Timeline: Research to Viable Product to Commercialization | 14 | 1 |
| Exhibit 1-2 NMEs and New BLAs Filed, 1996-2007 | 17 | 1 |
| Exhibit 1-3 Global R&D Spending, 1996-2007 | 17 | 1 |
| Exhibit 1-4 Global Drug Discovery Outsourcing Market 2005-2013 | 27 | 1 |
| Exhibit 2-1 Number of NMEs and New BLAs Filed 1996-2007 | 30 | 1 |
| Exhibit 2-3 Factors Involved in Making Outsourcing Decisions | 39 | 1 |
| Exhibit 3-1 The Drug Discovery Process | 42 | 1 |
| Exhibit 3-2 Drug Discovery Timeline: Research to Viable Product to Commercialization | 45 | 1 |
| Exhibit 3-4 Causes of New Drug Attrition | 48 | 1 |
| Exhibit 3-5 Drug Discovery Processes Frequently Outsourced | 51 | 1 |
| Exhibit 3-6 Bioinformatics as a Central Hub A Schematic of Discovery Disciplines and Methods | 53 | 1 |
| Exhibit 5-5 Market Share of the Segments within the Drug Discovery Market 2007 | 79 | 1 |
| Molecular modelling capabilities | 108 | 1 |
| Key Chart | 110 | 1 |
| Scope of services at Biology | 122 | 1 |
