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Sections |
| Title | Starting Page | Number of Pages |
|---|
| Table of Contents
Innovations in medical imaging
Executive Summary 10
Introduction 10
Current issues in medical imaging & recent breakthroughs 11
Challenges, opportunities & regulations 11
Market, trends & future directions 12
Chapter 1 Introduction 16
Wha | 0 | 1 |
| Table of Contents | 0 | 1 |
| Innovations in medical imaging | 0 | 1 |
| Executive Summary 10 | 0 | 1 |
| Introduction 10 | 0 | 1 |
| Current issues in medical imaging & recent breakthroughs 11 | 0 | 1 |
| Challenges, opportunities & regulations 11 | 0 | 1 |
| Market, trends & future directions 12 | 0 | 1 |
| Chapter 1 Introduction 16 | 0 | 1 |
| What does medical imaging encompass? 17 | 0 | 1 |
| Anatomical & functional imaging 20 | 0 | 1 |
| Why is medical imaging of value to the pharmaceutical industry? 21 | 0 | 1 |
| Applications of medical imaging in drug R&D 23 | 0 | 1 |
| Leading imaging modalities 26 | 0 | 1 |
| X-Ray 27 | 0 | 1 |
| Computed tomography 28 | 0 | 1 |
| Magnetic resonance imaging 30 | 0 | 1 |
| Functional MRI 31 | 0 | 1 |
| Optical near-infrared fluorescence imaging 32 | 0 | 1 |
| Ultrasound 34 | 0 | 1 |
| Nuclear medicine 35 | 0 | 1 |
| Positron Emission Tomography 35 | 0 | 1 |
| Single Photon Emission Computed Tomography 38 | 0 | 1 |
| Other imaging modalities 40 | 0 | 1 |
| Video imaging 40 | 0 | 1 |
| Comparison of imaging modalities: in vivo & ex vivo applications 41 | 0 | 1 |
| Advantages & disadvantages of imaging modalities 42 | 0 | 1 |
| Therapeutic applications 43 | 0 | 1 |
| Cancer 44 | 0 | 1 |
| Breast cancer 45 | 0 | 1 |
| Colorectal cancer 46 | 0 | 1 |
| Cardiovascular disease 46 | 0 | 1 |
| Coronary artery disease 46 | 0 | 1 |
| Stroke 47 | 0 | 1 |
| Other cardiovascular conditions 47 | 0 | 1 |
| Gastrointestinal conditions 48 | 0 | 1 |
| Orthopedics & osteoporosis 48 | 0 | 1 |
| CNS and thoracic trauma 48 | 0 | 1 |
| Therapeutic conclusions 48 | 0 | 1 |
| Chapter 2 Current issues in medical imaging & recent breakthroughs 52 | 0 | 1 |
| Pre-processing & post-processing issues 53 | 0 | 1 |
| Artifacts 54 | 0 | 1 |
| Noise 58 | 0 | 1 |
| Noise & artifact reduction 58 | 0 | 1 |
| Raw data acquisition & image reconstruction 58 | 0 | 1 |
| Image enhancement & portioning 59 | 0 | 1 |
| Conclusions on imaging issues 60 | 0 | 1 |
| Breakthroughs in medical imaging 60 | 0 | 1 |
| Novel imaging agents 62 | 0 | 1 |
| CT imaging agents 62 | 0 | 1 |
| MRI imaging agents 63 | 0 | 1 |
| Ultrasound imaging agents 64 | 0 | 1 |
| PET & SPECT imaging agents 65 | 0 | 1 |
| Imaging agent conclusions 67 | 0 | 1 |
| Novel scintillator & detectors 68 | 0 | 1 |
| Multimodality imaging devices 69 | 0 | 1 |
| SPECT-CT & PET-CT hybrids 69 | 0 | 1 |
| Spectral CT 72 | 0 | 1 |
| High field MRI 73 | 0 | 1 |
| Conclusions on imaging breakthroughs 75 | 0 | 1 |
| Chapter 3 Challenges, opportunities & regulations 78 | 0 | 1 |
| Geographical challenges & opportunities 80 | 0 | 1 |
| US market growth & legislative impact 80 | 0 | 1 |
| International markets and changing dynamics 82 | 0 | 1 |
| Urbanization and rise of the emerging markets 85 | 0 | 1 |
| Patient demographics: therapeutic dynamics 87 | 0 | 1 |
| Technical Challenges & Opportunities 89 | 0 | 1 |
| Molecular imaging 90 | 0 | 1 |
| Molecular imaging probes 92 | 0 | 1 |
| Regulatory support 93 | 0 | 1 |
| Molecular imaging consortia 93 | 0 | 1 |
| Imaging task forces 94 | 0 | 1 |
| Targeted and multifunctional imaging agents 96 | 0 | 1 |
| Nanotechnology 96 | 0 | 1 |
| Nano-enabled delivery 97 | 0 | 1 |
| Nano imaging materials 97 | 0 | 1 |
| Targeted contrast agents 98 | 0 | 1 |
| Multifunctional imaging agents 98 | 0 | 1 |
| Novel imaging modalities 99 | 0 | 1 |
| Magnetic Particle Imaging 99 | 0 | 1 |
| PET-MRI 102 | 0 | 1 |
| Real-time whole animal imaging 103 | 0 | 1 |
| Multi-spectral opto-acoustic tomography 106 | 0 | 1 |
| Computer assisted imaging & virtual surgery 107 | 0 | 1 |
| Virtual surgery 108 | 0 | 1 |
| Breakthrough conclusions 109 | 0 | 1 |
| Reimbursement & regulations 109 | 0 | 1 |
| Overall conclusions 111 | 0 | 1 |
| Chapter 4 Market trends & future directions 114 | 0 | 1 |
| The medical imaging market 115 | 0 | 1 |
| Leading manufacturers of medical imaging equipment 116 | 0 | 1 |
| Leading healthcare companies 119 | 0 | 1 |
| GE Healthcare, New York, US 119 | 0 | 1 |
| Hitachi Medical Corporation, Tokyo, Japan 119 | 0 | 1 |
| Philips Medical Systems, Amsterdam, The Netherlands 120 | 0 | 1 |
| Siemens Medical Solutions, Berlin & Munich, Germany 120 | 0 | 1 |
| Toshiba Medical Systems Corporation, Tokyo, Japan 121 | 0 | 1 |
| M&A activity 122 | 0 | 1 |
| Recent market trends 125 | 0 | 1 |
| Global trends in medical imaging 125 | 0 | 1 |
| Technological trends in imaging equipment 126 | 0 | 1 |
| Imaging agents & nanotechnology 126 | 0 | 1 |
| Image-guided radiation therapy and patient selection 127 | 0 | 1 |
| Future directions 128 | 0 | 1 |
| Molecular imaging & diagnostics 128 | 0 | 1 |
| Medical imaging informatics and networking 129 | 0 | 1 |
| Medical imaging and virtual reality 130 | 0 | 1 |
| Summary & overall conclusions 131 | 0 | 1 |
| Chapter 5 Appendices 134 | 0 | 1 |
| Primary research methodology 134 | 0 | 1 |
| Companies involved in medical imaging 135 | 0 | 1 |
| Glossary 136 | 0 | 1 |
| Acknowledgements 141 | 0 | 1 |
| Index 142 | 0 | 1 |
| Bibliography & Endnotes 143 | 0 | 1 |
| List of Figures | 0 | 1 |
| Figure 1.1: Medical imaging uses a spectrum of wavelengths 17 | 0 | 1 |
| Figure 1.2: Medical imaging technologies 19 | 0 | 1 |
| Figure 1.3: Imaging techniques and their uses 22 | 0 | 1 |
| Figure 1.4: Medical imaging in the drug discovery & development process 24 | 0 | 1 |
| Figure 1.5: X-ray of a skull a) anterior-posterior and b) lateral view 27 | 0 | 1 |
| Figure 1.6: Computed tomography of the head a) coronal section and b) sagittal section 28 | 0 | 1 |
| Figure 1.7: X-ray imagers 29 | 0 | 1 |
| Figure 1.8: Evolution of CT imaging 30 | 0 | 1 |
| Figure 1.9: Magnetic resonance imaging of the head 31 | 0 | 1 |
| Figure 1.10: Functional magnetic resonance imaging of the brain 32 | 0 | 1 |
| Figure 1.11: Multispectral imaging of the arm (700-900 nm range) 33 | 0 | 1 |
| Figure 1.12: Ultrasound image of a baby in-utero 34 | 0 | 1 |
| Figure 1.13: Principles of PET imaging 36 | 0 | 1 |
| Figure 1.14: Fused PET/CT image of anatomy and function 37
Figure 1.15: SPECT detection 39
Figure 1.16: video imaging 40
Figure 1.17: Therapeutic application of medical imaging 44
Figure 1.18: Therapeutic applications of medical imaging 49
Figure 2.19: Med | 0 | 1 |